Nitric oxide, NOC-12, and S-nitrosoglutathione modulate the skeletal muscle calcium release channel/ryanodine receptor by different mechanisms. An allosteric function for O2 in S-nitrosylation of the channel.
Sun J, Xu L, Eu JP, Stamler JS, Meissner G.
Sun J, et al. Among authors: meissner g.
J Biol Chem. 2003 Mar 7;278(10):8184-9. doi: 10.1074/jbc.M211940200. Epub 2002 Dec 30.
J Biol Chem. 2003.
PMID: 12509428
Free article.
P., Sun, J. H., Xu, L., Stamler, J. S., and Meissner, G. (2000) Cell 102, 499-509). Here we report that the NO donors NOC-12 and S-nitrosoglutathione both activate RyR1 by release of NO but do so independently of pO(2). ...
P., Sun, J. H., Xu, L., Stamler, J. S., and Meissner, G. (2000) Cell 102, 499-509). Here we report that the NO donors NOC-12 a …