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Effect of tyrosine kinase inhibitor STI571 on the kinase activity of wild-type and various mutated c-kit receptors found in mast cell neoplasms.
Zermati Y, De Sepulveda P, Féger F, Létard S, Kersual J, Castéran N, Gorochov G, Dy M, Ribadeau Dumas A, Dorgham K, Parizot C, Bieche Y, Vidaud M, Lortholary O, Arock M, Hermine O, Dubreuil P. Zermati Y, et al. Among authors: de sepulveda p. Oncogene. 2003 Feb 6;22(5):660-4. doi: 10.1038/sj.onc.1206120. Oncogene. 2003. PMID: 12569358
Signal transduction by several KIT juxtamembrane domain mutations.
Casteran N, De Sepulveda P, Beslu N, Aoubala M, Letard S, Lecocq E, Rottapel R, Dubreuil P. Casteran N, et al. Among authors: de sepulveda p. Oncogene. 2003 Jul 24;22(30):4710-22. doi: 10.1038/sj.onc.1206587. Oncogene. 2003. PMID: 12879016
KIT-D816V oncogenic activity is controlled by the juxtamembrane docking site Y568-Y570.
Chaix A, Arcangeli ML, Lopez S, Voisset E, Yang Y, Vita M, Letard S, Audebert S, Finetti P, Birnbaum D, Bertucci F, Aurrand-Lions M, Dubreuil P, De Sepulveda P. Chaix A, et al. Among authors: de sepulveda p. Oncogene. 2014 Feb 13;33(7):872-81. doi: 10.1038/onc.2013.12. Epub 2013 Feb 18. Oncogene. 2014. PMID: 23416972
The tumor suppressor activity of SOCS-1.
Rottapel R, Ilangumaran S, Neale C, La Rose J, Ho JM, Nguyen MH, Barber D, Dubreuil P, de Sepulveda P. Rottapel R, et al. Among authors: de sepulveda p. Oncogene. 2002 Jun 27;21(28):4351-62. doi: 10.1038/sj.onc.1205537. Oncogene. 2002. PMID: 12080466
Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology.
Hammam K, Saez-Ayala M, Rebuffet E, Gros L, Lopez S, Hajem B, Humbert M, Baudelet E, Audebert S, Betzi S, Lugari A, Combes S, Letard S, Casteran N, Mansfield C, Moussy A, De Sepulveda P, Morelli X, Dubreuil P. Hammam K, et al. Among authors: de sepulveda p. Nat Commun. 2017 Nov 10;8(1):1420. doi: 10.1038/s41467-017-01582-5. Nat Commun. 2017. PMID: 29127277 Free PMC article.
GlcNAc is a mast-cell chromatin-remodeling oncometabolite that promotes systemic mastocytosis aggressiveness.
Agopian J, Da Costa Q, Nguyen QV, Scorrano G, Kousteridou P, Yuan M, Chelbi R, Goubard A, Castellano R, Maurizio J, Teodosio C, De Sepulveda P, Asara JM, Orfao A, Hermine O, Dubreuil P, Brenet F. Agopian J, et al. Among authors: de sepulveda p. Blood. 2021 Oct 28;138(17):1590-1602. doi: 10.1182/blood.2020008948. Blood. 2021. PMID: 33974006 Free article.
40 results