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Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding.
Trapasso F, Krakowiak A, Cesari R, Arkles J, Yendamuri S, Ishii H, Vecchione A, Kuroki T, Bieganowski P, Pace HC, Huebner K, Croce CM, Brenner C. Trapasso F, et al. Among authors: brenner c. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1592-7. doi: 10.1073/pnas.0437915100. Epub 2003 Feb 6. Proc Natl Acad Sci U S A. 2003. PMID: 12574506 Free PMC article.
Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans.
Pekarsky Y, Campiglio M, Siprashvili Z, Druck T, Sedkov Y, Tillib S, Draganescu A, Wermuth P, Rothman JH, Huebner K, Buchberg AM, Mazo A, Brenner C, Croce CM. Pekarsky Y, et al. Among authors: brenner c. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8744-9. doi: 10.1073/pnas.95.15.8744. Proc Natl Acad Sci U S A. 1998. PMID: 9671749 Free PMC article.
The histidine triad superfamily of nucleotide-binding proteins.
Brenner C, Bieganowski P, Pace HC, Huebner K. Brenner C, et al. J Cell Physiol. 1999 Nov;181(2):179-87. doi: 10.1002/(SICI)1097-4652(199911)181:2<179::AID-JCP1>3.0.CO;2-8. J Cell Physiol. 1999. PMID: 10497298 Free PMC article. Review.
717 results