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Ferroptosis of select skin epithelial cells initiates and maintains chronic systemic immune-mediated psoriatic disease.
Vats K, Tian H, Singh K, Tyurina YY, Sparvero LJ, Tyurin VA, Kruglov O, Chang A, Wang J, Green F, Samovich SN, Zhang J, Chattopadhyay A, Murray N, Shah VK, Mathers AR, Chandran UR, Pilewski JM, Kellum JA, Wenzel SE, Bayir H, Kagan VE, Bunimovich YL. Vats K, et al. Among authors: kagan ve. J Clin Invest. 2024 Nov 21:e183219. doi: 10.1172/JCI183219. Online ahead of print. J Clin Invest. 2024. PMID: 39570671 Free article.
Mitochondrial bioenergetics and cardiolipin remodeling abnormalities in mitochondrial trifunctional protein deficiency.
Vieira Neto E, Wang M, Szuminsky AJ, Ferraro L, Koppes E, Wang Y, Van't Land C, Mohsen AW, Zanatta G, El-Gharbawy AH, Anthonymuthu TS, Tyurina YY, Tyurin VA, Kagan V, Bayır H, Vockley J. Vieira Neto E, et al. Among authors: kagan v. JCI Insight. 2024 Sep 10;9(17):e176887. doi: 10.1172/jci.insight.176887. JCI Insight. 2024. PMID: 39088276 Free PMC article.
Enhancing survival after ionizing radiation exposure through mitigation of pyroptosis.
Richter B, Epperly M, Tyurina Y, Shurin G, Johnson C, Korkmaz A, Gao Y, Scott J, Greenberger J, Kagan V, Bayır H. Richter B, et al. Among authors: kagan v. Biochim Biophys Acta Mol Basis Dis. 2024 Oct;1870(7):167434. doi: 10.1016/j.bbadis.2024.167434. Epub 2024 Jul 23. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 39053669
Targeted degradation of extracellular mitochondrial aspartyl-tRNA synthetase modulates immune responses.
Johnson BS, Farkas D, El-Mergawy R, Adair JA, Elhance A, Eltobgy M, Coan FM, Chafin L, Joseph JA, Cornwell A, Johns FJ, Rosas L, Rojas M, Farkas L, Bednash JS, Londino JD, Ray P, Ray A, Kagan V, Lee JS, Chen BB, Mallampalli RK. Johnson BS, et al. Among authors: kagan v. Nat Commun. 2024 Jul 22;15(1):6172. doi: 10.1038/s41467-024-50031-7. Nat Commun. 2024. PMID: 39039092 Free PMC article.
Compartmentalized mitochondrial ferroptosis converges with optineurin-mediated mitophagy to impact airway epithelial cell phenotypes and asthma outcomes.
Yamada K, St Croix C, Stolz DB, Tyurina YY, Tyurin VA, Bradley LR, Kapralov AA, Deng Y, Zhou X, Wei Q, Liao B, Fukuda N, Sullivan M, Trudeau J, Ray A, Kagan VE, Zhao J, Wenzel SE. Yamada K, et al. Among authors: kagan ve. Nat Commun. 2024 Jul 10;15(1):5818. doi: 10.1038/s41467-024-50222-2. Nat Commun. 2024. PMID: 38987265 Free PMC article.
Ferroptosis in health and disease.
Berndt C, Alborzinia H, Amen VS, Ayton S, Barayeu U, Bartelt A, Bayir H, Bebber CM, Birsoy K, Böttcher JP, Brabletz S, Brabletz T, Brown AR, Brüne B, Bulli G, Bruneau A, Chen Q, DeNicola GM, Dick TP, Distéfano A, Dixon SJ, Engler JB, Esser-von Bieren J, Fedorova M, Friedmann Angeli JP, Friese MA, Fuhrmann DC, García-Sáez AJ, Garbowicz K, Götz M, Gu W, Hammerich L, Hassannia B, Jiang X, Jeridi A, Kang YP, Kagan VE, Konrad DB, Kotschi S, Lei P, Le Tertre M, Lev S, Liang D, Linkermann A, Lohr C, Lorenz S, Luedde T, Methner A, Michalke B, Milton AV, Min J, Mishima E, Müller S, Motohashi H, Muckenthaler MU, Murakami S, Olzmann JA, Pagnussat G, Pan Z, Papagiannakopoulos T, Pedrera Puentes L, Pratt DA, Proneth B, Ramsauer L, Rodriguez R, Saito Y, Schmidt F, Schmitt C, Schulze A, Schwab A, Schwantes A, Soula M, Spitzlberger B, Stockwell BR, Thewes L, Thorn-Seshold O, Toyokuni S, Tonnus W, Trumpp A, Vandenabeele P, Vanden Berghe T, Venkataramani V, Vogel FCE, von Karstedt S, Wang F, Westermann F, Wientjens C, Wilhelm C, Wölk M, Wu K, Yang X, Yu F, Zou Y, Conrad M. Berndt C, et al. Among authors: kagan ve. Redox Biol. 2024 Sep;75:103211. doi: 10.1016/j.redox.2024.103211. Epub 2024 May 30. Redox Biol. 2024. PMID: 38908072 Free PMC article. Review.
703 results