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Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved.
Schröder NW, Morath S, Alexander C, Hamann L, Hartung T, Zähringer U, Göbel UB, Weber JR, Schumann RR. Schröder NW, et al. Among authors: alexander c. J Biol Chem. 2003 May 2;278(18):15587-94. doi: 10.1074/jbc.M212829200. Epub 2003 Feb 19. J Biol Chem. 2003. PMID: 12594207 Free article.
A fetal sheep liver extract containing immunostimulatory substances including LPS acts as leukocyte activator in cells of LPS responder and non responder mice.
Müller S, Hoffmann P, Esche UV, Mach JP, Gorczynski RM, Waelli T, Alexander C, Zähringer U, Rietschel ET, Bessler WG, Westphal O. Müller S, et al. Among authors: alexander c. Int Immunopharmacol. 2005 Dec;5(13-14):1809-19. doi: 10.1016/j.intimp.2005.05.011. Epub 2005 Jun 13. Int Immunopharmacol. 2005. PMID: 16275617
Three-dimensional mapping of differential amino acids of human, murine, canine and equine TLR4/MD-2 receptor complexes conferring endotoxic activation by lipid A, antagonism by Eritoran and species-dependent activities of Lipid IVA in the mammalian LPS sensor system.
Scior T, Lozano-Aponte J, Figueroa-Vazquez V, Yunes-Rojas JA, Zähringer U, Alexander C. Scior T, et al. Among authors: alexander c. Comput Struct Biotechnol J. 2013 Aug 8;7:e201305003. doi: 10.5936/csbj.201305003. eCollection 2013. Comput Struct Biotechnol J. 2013. PMID: 24688739 Free PMC article.
1,719 results