Geacintov NE - Search Results

1

Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa.

Huang X, Kolbanovskiy A, Wu X, Zhang Y, Wang Z, Zhuang P, Amin S, Geacintov NE. Huang X, et al. Among authors: geacintov ne. Biochemistry. 2003 Mar 4;42(8):2456-66. doi: 10.1021/bi026912q. Biochemistry. 2003. PMID: 12600213

2

Fluorescence characteristics of site-specific and stereochemically distinct benzo[a]pyrene diol epoxide-DNA adducts as probes of adduct conformation.

Huang W, Amin S, Geacintov NE. Huang W, et al. Among authors: geacintov ne. Chem Res Toxicol. 2002 Feb;15(2):118-26. doi: 10.1021/tx010135y. Chem Res Toxicol. 2002. PMID: 11849037

3

Synthesis and characterization of site-specific and stereoisomeric fjord dibenzo[a,l]pyrene diol epoxide-N(6)-adenine adducts: unusual thermal stabilization of modified DNA duplexes.

Ruan Q, Kolbanovskiy A, Zhuang P, Chen J, Krzeminski J, Amin S, Geacintov NE. Ruan Q, et al. Among authors: geacintov ne. Chem Res Toxicol. 2002 Feb;15(2):249-61. doi: 10.1021/tx010157k. Chem Res Toxicol. 2002. PMID: 11849052

4

Conformational changes of a benzo[a]pyrene diol epoxide-N(2)-dG adduct induced by a 5'-flanking 5-methyl-substituted cytosine in a (Me)CG double-stranded oligonucleotide sequence context.

Huang X, Colgate KC, Kolbanovskiy A, Amin S, Geacintov NE. Huang X, et al. Among authors: geacintov ne. Chem Res Toxicol. 2002 Mar;15(3):438-44. doi: 10.1021/tx015588h. Chem Res Toxicol. 2002. PMID: 11896693

5

Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

Suzuki N, Ohashi E, Kolbanovskiy A, Geacintov NE, Grollman AP, Ohmori H, Shibutani S. Suzuki N, et al. Among authors: geacintov ne. Biochemistry. 2002 May 14;41(19):6100-6. doi: 10.1021/bi020049c. Biochemistry. 2002. PMID: 11994005

6

trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases.

Rechkoblit O, Zhang Y, Guo D, Wang Z, Amin S, Krzeminsky J, Louneva N, Geacintov NE. Rechkoblit O, et al. Among authors: geacintov ne. J Biol Chem. 2002 Aug 23;277(34):30488-94. doi: 10.1074/jbc.M201167200. Epub 2002 Jun 12. J Biol Chem. 2002. PMID: 12063247 Free article.

7

Sequence context- and temperature-dependent nucleotide excision repair of a benzo[a]pyrene diol epoxide-guanine DNA adduct catalyzed by thermophilic UvrABC proteins.

Ruan Q, Liu T, Kolbanovskiy A, Liu Y, Ren J, Skorvaga M, Zou Y, Lader J, Malkani B, Amin S, Van Houten B, Geacintov NE. Ruan Q, et al. Among authors: geacintov ne. Biochemistry. 2007 Jun 12;46(23):7006-15. doi: 10.1021/bi700294k. Epub 2007 May 17. Biochemistry. 2007. PMID: 17506530

8

Nuclear magnetic resonance studies of an N2-guanine adduct derived from the tumorigen dibenzo[a,l]pyrene in DNA: impact of adduct stereochemistry, size, and local DNA sequence on solution conformations.

Rodríguez FA, Liu Z, Lin CH, Ding S, Cai Y, Kolbanovskiy A, Kolbanovskiy M, Amin S, Broyde S, Geacintov NE. Rodríguez FA, et al. Among authors: geacintov ne. Biochemistry. 2014 Mar 25;53(11):1827-41. doi: 10.1021/bi4017044. Epub 2014 Mar 11. Biochemistry. 2014. PMID: 24617538 Free PMC article.

9

Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality.

Moriya M, Spiegel S, Fernandes A, Amin S, Liu T, Geacintov N, Grollman AP. Moriya M, et al. Biochemistry. 1996 Dec 24;35(51):16646-51. doi: 10.1021/bi9608875. Biochemistry. 1996. PMID: 8988000

10

Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.

Feng B, Gorin A, Kolbanovskiy A, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Feng B, et al. Among authors: geacintov ne. Biochemistry. 1997 Nov 11;36(45):13780-90. doi: 10.1021/bi970070r. Biochemistry. 1997. PMID: 9374854

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