Hose C - Search Results

1

Genotoxic profiling of MCF-7 breast cancer cell line elucidates gene expression modifications underlying toxicity of the anticancer drug 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole.

Monks A, Harris E, Hose C, Connelly J, Sausville EA. Monks A, et al. Among authors: hose c. Mol Pharmacol. 2003 Mar;63(3):766-72. doi: 10.1124/mol.63.3.766. Mol Pharmacol. 2003. PMID: 12606787

2

Induction of CYP1A1 in tumor cells by the antitumor agent 2-[4-amino-3-methylphenyl]-5-fluoro-benzothiazole: a potential surrogate marker for patient sensitivity.

Hose CD, Hollingshead M, Sausville EA, Monks A. Hose CD, et al. Mol Cancer Ther. 2003 Dec;2(12):1265-72. Mol Cancer Ther. 2003. PMID: 14707267

3

The antitumor drug candidate 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole induces NF-kappaB activity in drug-sensitive MCF-7 cells.

Brantley E, Patel V, Stinson SF, Trapani V, Hose CD, Ciolino HP, Yeh GC, Gutkind JS, Sausville EA, Loaiza-Pérez AI. Brantley E, et al. Among authors: hose cd. Anticancer Drugs. 2005 Feb;16(2):137-43. doi: 10.1097/00001813-200502000-00004. Anticancer Drugs. 2005. PMID: 15655410

4

Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole.

Loaiza-Pérez AI, Trapani V, Hose C, Singh SS, Trepel JB, Stevens MF, Bradshaw TD, Sausville EA. Loaiza-Pérez AI, et al. Among authors: hose c. Mol Pharmacol. 2002 Jan;61(1):13-9. doi: 10.1124/mol.61.1.13. Mol Pharmacol. 2002. PMID: 11752201

5

Transcriptional profiling identifies altered intracellular labile iron homeostasis as a contributing factor to the toxicity of adaphostin: decreased vascular endothelial growth factor secretion is independent of hypoxia-inducible factor-1 regulation.

Hose C, Kaur G, Sausville EA, Monks A. Hose C, et al. Clin Cancer Res. 2005 Sep 1;11(17):6370-81. doi: 10.1158/1078-0432.CCR-05-0291. Clin Cancer Res. 2005. PMID: 16144942

6

Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells.

Brantley E, Trapani V, Alley MC, Hose CD, Bradshaw TD, Stevens MF, Sausville EA, Stinson SF. Brantley E, et al. Among authors: hose cd. Drug Metab Dispos. 2004 Dec;32(12):1392-401. doi: 10.1124/dmd.104.001057. Epub 2004 Sep 8. Drug Metab Dispos. 2004. PMID: 15355884

7

Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts.

Monks A, Hose CD, Pezzoli P, Kondapaka S, Vansant G, Petersen KD, Sehested M, Monforte J, Shoemaker RH. Monks A, et al. Anticancer Drugs. 2009 Sep;20(8):682-92. doi: 10.1097/CAD.0b013e32832e14e1. Anticancer Drugs. 2009. PMID: 19606018

8

Aryl hydrocarbon receptor activation of an antitumor aminoflavone: basis of selective toxicity for MCF-7 breast tumor cells.

Loaiza-Pérez AI, Kenney S, Boswell J, Hollingshead M, Alley MC, Hose C, Ciolino HP, Yeh GC, Trepel JB, Vistica DT, Sausville EA. Loaiza-Pérez AI, et al. Among authors: hose c. Mol Cancer Ther. 2004 Jun;3(6):715-25. Mol Cancer Ther. 2004. PMID: 15210858

9

Drug-induced expression of nonsteroidal anti-inflammatory drug-activated gene/macrophage inhibitory cytokine-1/prostate-derived factor, a putative tumor suppressor, inhibits tumor growth.

Martinez JM, Sali T, Okazaki R, Anna C, Hollingshead M, Hose C, Monks A, Walker NJ, Baek SJ, Eling TE. Martinez JM, et al. Among authors: hose c. J Pharmacol Exp Ther. 2006 Aug;318(2):899-906. doi: 10.1124/jpet.105.100081. Epub 2006 May 19. J Pharmacol Exp Ther. 2006. PMID: 16714403

10

The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel.

Monks A, Zhao Y, Hose C, Hamed H, Krushkal J, Fang J, Sonkin D, Palmisano A, Polley EC, Fogli LK, Konaté MM, Miller SB, Simpson MA, Voth AR, Li MC, Harris E, Wu X, Connelly JW, Rapisarda A, Teicher BA, Simon R, Doroshow JH. Monks A, et al. Among authors: hose c. Cancer Res. 2018 Dec 15;78(24):6807-6817. doi: 10.1158/0008-5472.CAN-18-0989. Epub 2018 Oct 24. Cancer Res. 2018. PMID: 30355619 Free PMC article.

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