Monks A - Search Results

1

Genotoxic profiling of MCF-7 breast cancer cell line elucidates gene expression modifications underlying toxicity of the anticancer drug 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole.

Monks A, Harris E, Hose C, Connelly J, Sausville EA. Monks A, et al. Mol Pharmacol. 2003 Mar;63(3):766-72. doi: 10.1124/mol.63.3.766. Mol Pharmacol. 2003. PMID: 12606787

2

Induction of CYP1A1 in tumor cells by the antitumor agent 2-[4-amino-3-methylphenyl]-5-fluoro-benzothiazole: a potential surrogate marker for patient sensitivity.

Hose CD, Hollingshead M, Sausville EA, Monks A. Hose CD, et al. Among authors: monks a. Mol Cancer Ther. 2003 Dec;2(12):1265-72. Mol Cancer Ther. 2003. PMID: 14707267

3

Transcriptional profiling identifies altered intracellular labile iron homeostasis as a contributing factor to the toxicity of adaphostin: decreased vascular endothelial growth factor secretion is independent of hypoxia-inducible factor-1 regulation.

Hose C, Kaur G, Sausville EA, Monks A. Hose C, et al. Among authors: monks a. Clin Cancer Res. 2005 Sep 1;11(17):6370-81. doi: 10.1158/1078-0432.CCR-05-0291. Clin Cancer Res. 2005. PMID: 16144942

4

Differential gene expression as a potential classifier of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole-sensitive and -insensitive cell lines.

Wallqvist A, Connelly J, Sausville EA, Covell DG, Monks A. Wallqvist A, et al. Among authors: monks a. Mol Pharmacol. 2006 Mar;69(3):737-48. doi: 10.1124/mol.105.017061. Epub 2005 Dec 6. Mol Pharmacol. 2006. PMID: 16332985

5

Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol.

Lam LT, Pickeral OK, Peng AC, Rosenwald A, Hurt EM, Giltnane JM, Averett LM, Zhao H, Davis RE, Sathyamoorthy M, Wahl LM, Harris ED, Mikovits JA, Monks AP, Hollingshead MG, Sausville EA, Staudt LM. Lam LT, et al. Among authors: monks ap. Genome Biol. 2001;2(10):RESEARCH0041. doi: 10.1186/gb-2001-2-10-research0041. Epub 2001 Sep 13. Genome Biol. 2001. PMID: 11597333 Free PMC article.

6

Drug-induced expression of nonsteroidal anti-inflammatory drug-activated gene/macrophage inhibitory cytokine-1/prostate-derived factor, a putative tumor suppressor, inhibits tumor growth.

Martinez JM, Sali T, Okazaki R, Anna C, Hollingshead M, Hose C, Monks A, Walker NJ, Baek SJ, Eling TE. Martinez JM, et al. Among authors: monks a. J Pharmacol Exp Ther. 2006 Aug;318(2):899-906. doi: 10.1124/jpet.105.100081. Epub 2006 May 19. J Pharmacol Exp Ther. 2006. PMID: 16714403

7

Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts.

Monks A, Hose CD, Pezzoli P, Kondapaka S, Vansant G, Petersen KD, Sehested M, Monforte J, Shoemaker RH. Monks A, et al. Anticancer Drugs. 2009 Sep;20(8):682-92. doi: 10.1097/CAD.0b013e32832e14e1. Anticancer Drugs. 2009. PMID: 19606018

8

Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression.

Teicher BA, Polley E, Kunkel M, Evans D, Silvers T, Delosh R, Laudeman J, Ogle C, Reinhart R, Selby M, Connelly J, Harris E, Monks A, Morris J. Teicher BA, et al. Among authors: monks a. Mol Cancer Ther. 2015 Nov;14(11):2452-62. doi: 10.1158/1535-7163.MCT-15-0074. Epub 2015 Sep 8. Mol Cancer Ther. 2015. PMID: 26351324 Free PMC article.

9

The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel.

Monks A, Zhao Y, Hose C, Hamed H, Krushkal J, Fang J, Sonkin D, Palmisano A, Polley EC, Fogli LK, Konaté MM, Miller SB, Simpson MA, Voth AR, Li MC, Harris E, Wu X, Connelly JW, Rapisarda A, Teicher BA, Simon R, Doroshow JH. Monks A, et al. Cancer Res. 2018 Dec 15;78(24):6807-6817. doi: 10.1158/0008-5472.CAN-18-0989. Epub 2018 Oct 24. Cancer Res. 2018. PMID: 30355619 Free PMC article.

10

Identification of pharmacodynamic biomarkers and common molecular mechanisms of response to genotoxic agents in cancer cell lines.

Min DJ, Zhao Y, Monks A, Palmisano A, Hose C, Teicher BA, Doroshow JH, Simon RM. Min DJ, et al. Among authors: monks a. Cancer Chemother Pharmacol. 2019 Oct;84(4):771-780. doi: 10.1007/s00280-019-03898-z. Epub 2019 Jul 31. Cancer Chemother Pharmacol. 2019. PMID: 31367787 Free PMC article.

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