Roper JR - Search Results

1

High-resolution crystal structure of Trypanosoma brucei UDP-galactose 4'-epimerase: a potential target for structure-based development of novel trypanocides.

Shaw MP, Bond CS, Roper JR, Gourley DG, Ferguson MA, Hunter WN. Shaw MP, et al. Among authors: roper jr. Mol Biochem Parasitol. 2003 Feb;126(2):173-80. doi: 10.1016/s0166-6851(02)00243-8. Mol Biochem Parasitol. 2003. PMID: 12615316

2

Galactose metabolism is essential for the African sleeping sickness parasite Trypanosoma brucei.

Roper JR, Guther ML, Milne KG, Ferguson MA. Roper JR, et al. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):5884-9. doi: 10.1073/pnas.092669999. Proc Natl Acad Sci U S A. 2002. PMID: 11983889 Free PMC article.

3

Cloning and characterisation of the UDP-glucose 4'-epimerase of Trypanosoma cruzi.

Roper JR, Ferguson MA. Roper JR, et al. Mol Biochem Parasitol. 2003 Nov;132(1):47-53. doi: 10.1016/j.molbiopara.2003.07.002. Mol Biochem Parasitol. 2003. PMID: 14563536

4

The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number.

Roper JR, Güther ML, Macrae JI, Prescott AR, Hallyburton I, Acosta-Serrano A, Ferguson MA. Roper JR, et al. J Biol Chem. 2005 May 20;280(20):19728-36. doi: 10.1074/jbc.M502370200. Epub 2005 Mar 14. J Biol Chem. 2005. PMID: 15767252 Free article.

5

The suppression of galactose metabolism in Trypanosoma cruzi epimastigotes causes changes in cell surface molecular architecture and cell morphology.

MacRae JI, Obado SO, Turnock DC, Roper JR, Kierans M, Kelly JM, Ferguson MA. MacRae JI, et al. Among authors: roper jr. Mol Biochem Parasitol. 2006 May;147(1):126-36. doi: 10.1016/j.molbiopara.2006.02.011. Epub 2006 Mar 9. Mol Biochem Parasitol. 2006. PMID: 16569451

6

Engineered gene over-expression as a method of drug target identification.

Sugden CJ, Roper JR, Williams JG. Sugden CJ, et al. Among authors: roper jr. Biochem Biophys Res Commun. 2005 Aug 26;334(2):555-60. doi: 10.1016/j.bbrc.2005.06.117. Biochem Biophys Res Commun. 2005. PMID: 16005849

7

The Schiff base complex of yeast 5-aminolaevulinic acid dehydratase with laevulinic acid.

Erskine PT, Newbold R, Roper J, Coker A, Warren MJ, Shoolingin-Jordan PM, Wood SP, Cooper JB. Erskine PT, et al. Protein Sci. 1999 Jun;8(6):1250-6. doi: 10.1110/ps.8.6.1250. Protein Sci. 1999. PMID: 10386874 Free PMC article.

8

Target localization using scanner-acquired SPECT data.

Roper JR, Bowsher JE, Wilson JM, Turkington TG, Yin FF. Roper JR, et al. J Appl Clin Med Phys. 2012 May 10;13(3):3724. doi: 10.1120/jacmp.v13i3.3724. J Appl Clin Med Phys. 2012. PMID: 22584168 Free PMC article.

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