Bachmann K - Search Results

1

Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of ethosuximide by human hepatic microsomal enzymes.

Bachmann K, He Y, Sarver JG, Peng N. Bachmann K, et al. Xenobiotica. 2003 Mar;33(3):265-76. doi: 10.1080/0049825021000061606. Xenobiotica. 2003. PMID: 12637244

2

Ethosuximide is primarily metabolized by CYP3A when incubated with isolated rat liver microsomes.

Sarver JG, Bachmann KA, Zhu D, Klis WA. Sarver JG, et al. Among authors: bachmann ka. Drug Metab Dispos. 1998 Jan;26(1):78-82. Drug Metab Dispos. 1998. PMID: 9443857

3

Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans.

Bachmann K, Sarver JG. Bachmann K, et al. Pharmacology. 1996 Mar;52(3):169-77. doi: 10.1159/000139381. Pharmacology. 1996. PMID: 8849486

4

Estimating xenobiotic half-lives in humans from rat data: influence of log P.

Sarver JG, White D, Erhardt P, Bachmann K. Sarver JG, et al. Among authors: bachmann k. Environ Health Perspect. 1997 Nov;105(11):1204-9. doi: 10.1289/ehp.971051204. Environ Health Perspect. 1997. PMID: 9370523 Free PMC article. Review.

5

Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo.

Bachmann KA, Jauregui L. Bachmann KA, et al. Xenobiotica. 1993 Mar;23(3):307-15. doi: 10.3109/00498259309059384. Xenobiotica. 1993. PMID: 8498093 Clinical Trial.

6

The use of single sample clearance estimates to probe hepatic drug metabolism: handprinting the influence of phenobarbitone on human hepatic drug metabolism.

Bachmann KA, Nunlee M, Martin M, Jaregui L. Bachmann KA, et al. Xenobiotica. 1991 Oct;21(10):1385-92. doi: 10.3109/00498259109043213. Xenobiotica. 1991. PMID: 1796615

7

Prediction of in vivo hepatic clearance from in vitro data using cryopreserved human hepatocytes.

Bachmann K, Byers J, Ghosh R. Bachmann K, et al. Xenobiotica. 2003 May;33(5):475-83. doi: 10.1080/0049825031000076177. Xenobiotica. 2003. PMID: 12746104

8

The use of single sample clearance estimates to probe hepatic drug metabolism: handprinting the influence of cigarette smoking on human hepatic drug metabolism.

Bachmann KA, Nunlee M, Martin M, Schwartz J, Jauregui L, Forney RB Jr. Bachmann KA, et al. Xenobiotica. 1990 May;20(5):537-47. doi: 10.3109/00498259009046868. Xenobiotica. 1990. PMID: 2112290

9

The use of single-sample clearance estimates to probe hepatic drug metabolism in rats. IV. A model for possible application to phenotyping xenobiotic influences on human drug metabolism.

Bachmann KA. Bachmann KA. Xenobiotica. 1989 Dec;19(12):1449-59. doi: 10.3109/00498258909043195. Xenobiotica. 1989. PMID: 2618092

10

Ethosuximide disposition kinetics in rats.

Bachmann K, Jahn D, Yang C, Schwartz J. Bachmann K, et al. Xenobiotica. 1988 Apr;18(4):373-80. doi: 10.3109/00498258809041673. Xenobiotica. 1988. PMID: 3400266

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