Kluijtmans LA - Search Results

1

Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.

Kluijtmans LA, Young IS, Boreham CA, Murray L, McMaster D, McNulty H, Strain JJ, McPartlin J, Scott JM, Whitehead AS. Kluijtmans LA, et al. Blood. 2003 Apr 1;101(7):2483-8. doi: 10.1182/blood.V101.7.2483. Blood. 2003. PMID: 12642343 Free article.

2

The 5,10-methylenetetrahydrofolate reductase C677T polymorphism interacts with smoking to increase homocysteine.

Brown KS, Kluijtmans LA, Young IS, Murray L, McMaster D, Woodside JV, Yarnell JW, Boreham CA, McNulty H, Strain JJ, McPartlin J, Scott JM, Mitchell LE, Whitehead AS. Brown KS, et al. Among authors: kluijtmans la. Atherosclerosis. 2004 Jun;174(2):315-22. doi: 10.1016/j.atherosclerosis.2004.01.023. Atherosclerosis. 2004. PMID: 15136061 Clinical Trial.

3

Genetic evidence that nitric oxide modulates homocysteine: the NOS3 894TT genotype is a risk factor for hyperhomocystenemia.

Brown KS, Kluijtmans LA, Young IS, Woodside J, Yarnell JW, McMaster D, Murray L, Evans AE, Boreham CA, McNulty H, Strain JJ, Mitchell LE, Whitehead AS. Brown KS, et al. Among authors: kluijtmans la. Arterioscler Thromb Vasc Biol. 2003 Jun 1;23(6):1014-20. doi: 10.1161/01.ATV.0000071348.70527.F4. Epub 2003 Apr 10. Arterioscler Thromb Vasc Biol. 2003. PMID: 12689917

4

The thymidylate synthase tandem repeat polymorphism is not associated with homocysteine concentrations in healthy young subjects.

Brown KS, Kluijtmans LA, Young IS, McNulty H, Mitchell LE, Yarnell JW, Woodside JV, Boreham CA, McMaster D, Murray L, Strain JJ, Whitehead AS. Brown KS, et al. Among authors: kluijtmans la. Hum Genet. 2004 Jan;114(2):182-5. doi: 10.1007/s00439-003-1039-9. Epub 2003 Oct 25. Hum Genet. 2004. PMID: 14586640

5

Accurate and rapid "multiplex heteroduplexing" method for genotyping key enzymes involved in folate/homocysteine metabolism.

Barbaux S, Kluijtmans LA, Whitehead AS. Barbaux S, et al. Among authors: kluijtmans la. Clin Chem. 2000 Jul;46(7):907-12. Clin Chem. 2000. PMID: 10894832

6

Methylenetetrahydrofolate reductase genotypes and predisposition to atherothrombotic disease; evidence that all three MTHFR C677T genotypes confer different levels of risk.

Kluijtmans LA, Whitehead AS. Kluijtmans LA, et al. Eur Heart J. 2001 Feb;22(4):294-9. doi: 10.1053/euhj.2000.2239. Eur Heart J. 2001. PMID: 11161947

7

The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations.

Gaughan DJ, Kluijtmans LA, Barbaux S, McMaster D, Young IS, Yarnell JW, Evans A, Whitehead AS. Gaughan DJ, et al. Among authors: kluijtmans la. Atherosclerosis. 2001 Aug;157(2):451-6. doi: 10.1016/s0021-9150(00)00739-5. Atherosclerosis. 2001. PMID: 11472746

8

The human and mouse methylenetetrahydrofolate reductase (MTHFR) genes: genomic organization, mRNA structure and linkage to the CLCN6 gene.

Gaughan DJ, Barbaux S, Kluijtmans LA, Whitehead AS. Gaughan DJ, et al. Among authors: kluijtmans la. Gene. 2000 Oct 31;257(2):279-89. doi: 10.1016/s0378-1119(00)00392-9. Gene. 2000. PMID: 11080594 Free article.

9

Phase I clinical and pharmacogenetic trial of irinotecan and raltitrexed administered every 21 days to patients with cancer.

Stevenson JP, Redlinger M, Kluijtmans LA, Sun W, Algazy K, Giantonio B, Haller DG, Hardy C, Whitehead AS, O'Dwyer PJ. Stevenson JP, et al. Among authors: kluijtmans la. J Clin Oncol. 2001 Oct 15;19(20):4081-7. doi: 10.1200/JCO.2001.19.20.4081. J Clin Oncol. 2001. PMID: 11600611 Clinical Trial.

10

Alcohol increases homocysteine and reduces B vitamin concentration in healthy male volunteers--a randomized, crossover intervention study.

Gibson A, Woodside JV, Young IS, Sharpe PC, Mercer C, Patterson CC, McKinley MC, Kluijtmans LA, Whitehead AS, Evans A. Gibson A, et al. Among authors: kluijtmans la. QJM. 2008 Nov;101(11):881-7. doi: 10.1093/qjmed/hcn112. Epub 2008 Sep 12. QJM. 2008. PMID: 18790817 Free PMC article. Clinical Trial.

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