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Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein.
Aron JL, Parthun MR, Marcucci G, Kitada S, Mone AP, Davis ME, Shen T, Murphy T, Wickham J, Kanakry C, Lucas DM, Reed JC, Grever MR, Byrd JC. Aron JL, et al. Among authors: grever mr. Blood. 2003 Jul 15;102(2):652-8. doi: 10.1182/blood-2002-12-3794. Epub 2003 Mar 20. Blood. 2003. PMID: 12649137 Free article.
Introduction: chronic lymphocytic leukemia.
Byrd JC, Flinn IW, Grever MR. Byrd JC, et al. Among authors: grever mr. Semin Oncol. 1998 Feb;25(1):4-5. Semin Oncol. 1998. PMID: 9482520 No abstract available.
323 results