Uhl GR - Search Results

1

Phosphatidylinositol 3-kinase, protein kinase C, and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites.

Lin Z, Zhang PW, Zhu X, Melgari JM, Huff R, Spieldoch RL, Uhl GR. Lin Z, et al. Among authors: uhl gr. J Biol Chem. 2003 May 30;278(22):20162-70. doi: 10.1074/jbc.M209584200. Epub 2003 Mar 26. J Biol Chem. 2003. PMID: 12660249 Free article.

2

Human dopamine transporter gene variation: effects of protein coding variants V55A and V382A on expression and uptake activities.

Lin Z, Uhl GR. Lin Z, et al. Among authors: uhl gr. Pharmacogenomics J. 2003;3(3):159-68. doi: 10.1038/sj.tpj.6500169. Pharmacogenomics J. 2003. PMID: 12815364

3

The top 20 dopamine transporter mutants: structure-function relationships and cocaine actions.

Uhl GR, Lin Z. Uhl GR, et al. Eur J Pharmacol. 2003 Oct 31;479(1-3):71-82. doi: 10.1016/j.ejphar.2003.08.058. Eur J Pharmacol. 2003. PMID: 14612139 Review.

4

Dopamine transporter mutants with cocaine resistance and normal dopamine uptake provide targets for cocaine antagonism.

Lin Z, Uhl GR. Lin Z, et al. Among authors: uhl gr. Mol Pharmacol. 2002 Apr;61(4):885-91. doi: 10.1124/mol.61.4.885. Mol Pharmacol. 2002. PMID: 11901228

5

Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes.

Vaughan RA, Huff RA, Uhl GR, Kuhar MJ. Vaughan RA, et al. Among authors: uhl gr. J Biol Chem. 1997 Jun 13;272(24):15541-6. doi: 10.1074/jbc.272.24.15541. J Biol Chem. 1997. PMID: 9182590 Free article.

6

KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine.

Liu QR, Zhang PW, Zhen Q, Walther D, Wang XB, Uhl GR. Liu QR, et al. Among authors: uhl gr. J Biol Chem. 2002 Apr 12;277(15):13312-20. doi: 10.1074/jbc.M107558200. Epub 2002 Jan 25. J Biol Chem. 2002. PMID: 11812771 Free article.

7

GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA.

Liu QR, Zhang PW, Lin Z, Li QF, Woods AS, Troncoso J, Uhl GR. Liu QR, et al. Among authors: uhl gr. Biochem J. 2004 Jan 1;377(Pt 1):171-81. doi: 10.1042/BJ20030128. Biochem J. 2004. PMID: 12974676 Free PMC article.

8

Proline mutations induce negative-dosage effects on uptake velocity of the dopamine transporter.

Lin Z, Uhl GR. Lin Z, et al. Among authors: uhl gr. J Neurochem. 2005 Jul;94(1):276-87. doi: 10.1111/j.1471-4159.2005.03196.x. J Neurochem. 2005. PMID: 15953370 Free article.

9

Dopamine efflux via wild-type and mutant dopamine transporters: alanine substitution for proline-572 enhances efflux and reduces dependence on extracellular dopamine, sodium and chloride concentrations.

Itokawa M, Lin Z, Uhl GR. Itokawa M, et al. Among authors: uhl gr. Brain Res Mol Brain Res. 2002 Dec;108(1-2):71-80. doi: 10.1016/s0169-328x(02)00515-6. Brain Res Mol Brain Res. 2002. PMID: 12480180

10

Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax.

Huff RA, Vaughan RA, Kuhar MJ, Uhl GR. Huff RA, et al. Among authors: uhl gr. J Neurochem. 1997 Jan;68(1):225-32. doi: 10.1046/j.1471-4159.1997.68010225.x. J Neurochem. 1997. PMID: 8978729 Free article.

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