Lichtenthaler SF - Search Results

1

No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the beta-cleaved C-terminal APP fragment.

Rutten BP, Wirths O, Van de Berg WD, Lichtenthaler SF, Vehoff J, Steinbusch HW, Korr H, Beyreuther K, Multhaup G, Bayer TA, Schmitz C. Rutten BP, et al. Among authors: lichtenthaler sf. Neurobiol Dis. 2003 Mar;12(2):110-20. doi: 10.1016/s0969-9961(02)00015-3. Neurobiol Dis. 2003. PMID: 12667466

2

Mutations in the transmembrane domain of APP altering gamma-secretase specificity.

Lichtenthaler SF, Ida N, Multhaup G, Masters CL, Beyreuther K. Lichtenthaler SF, et al. Biochemistry. 1997 Dec 9;36(49):15396-403. doi: 10.1021/bi971071m. Biochemistry. 1997. PMID: 9398269

3

Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein.

Lichtenthaler SF, Wang R, Grimm H, Uljon SN, Masters CL, Beyreuther K. Lichtenthaler SF, et al. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3053-8. doi: 10.1073/pnas.96.6.3053. Proc Natl Acad Sci U S A. 1999. PMID: 10077635 Free PMC article.

4

A novel substrate for analyzing Alzheimer's disease gamma-secretase.

Lichtenthaler SF, Multhaup G, Masters CL, Beyreuther K. Lichtenthaler SF, et al. FEBS Lett. 1999 Jun 25;453(3):288-92. doi: 10.1016/s0014-5793(99)00730-9. FEBS Lett. 1999. PMID: 10405162 Free article.

5

The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain.

Lichtenthaler SF, Beher D, Grimm HS, Wang R, Shearman MS, Masters CL, Beyreuther K. Lichtenthaler SF, et al. Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1365-70. doi: 10.1073/pnas.032395699. Epub 2002 Jan 22. Proc Natl Acad Sci U S A. 2002. PMID: 11805291 Free PMC article.

6

The transmembrane domain of the amyloid precursor protein in microsomal membranes is on both sides shorter than predicted.

Grziwa B, Grimm MO, Masters CL, Beyreuther K, Hartmann T, Lichtenthaler SF. Grziwa B, et al. Among authors: lichtenthaler sf. J Biol Chem. 2003 Feb 28;278(9):6803-8. doi: 10.1074/jbc.M210047200. Epub 2002 Nov 25. J Biol Chem. 2003. PMID: 12454010 Free article.

7

gamma-Secretase cleavage site specificity differs for intracellular and secretory amyloid beta.

Grimm HS, Beher D, Lichtenthaler SF, Shearman MS, Beyreuther K, Hartmann T. Grimm HS, et al. Among authors: lichtenthaler sf. J Biol Chem. 2003 Apr 11;278(15):13077-85. doi: 10.1074/jbc.M210380200. Epub 2003 Jan 29. J Biol Chem. 2003. PMID: 12556458 Free article.

8

Dimerization of beta-site beta-amyloid precursor protein-cleaving enzyme.

Westmeyer GG, Willem M, Lichtenthaler SF, Lurman G, Multhaup G, Assfalg-Machleidt I, Reiss K, Saftig P, Haass C. Westmeyer GG, et al. Among authors: lichtenthaler sf. J Biol Chem. 2004 Dec 17;279(51):53205-12. doi: 10.1074/jbc.M410378200. Epub 2004 Oct 12. J Biol Chem. 2004. PMID: 15485862 Free article.

9

Alzheimer's disease: correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome.

Christie G, Markwell RE, Gray CW, Smith L, Godfrey F, Mansfield F, Wadsworth H, King R, McLaughlin M, Cooper DG, Ward RV, Howlett DR, Hartmann T, Lichtenthaler SF, Beyreuther K, Underwood J, Gribble SK, Cappai R, Masters CL, Tamaoka A, Gardner RL, Rivett AJ, Karran EH, Allsop D. Christie G, et al. Among authors: lichtenthaler sf. J Neurochem. 1999 Jul;73(1):195-204. doi: 10.1046/j.1471-4159.1999.0730195.x. J Neurochem. 1999. PMID: 10386971 Free article.

10

Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines.

Colombo A, Wang H, Kuhn PH, Page R, Kremmer E, Dempsey PJ, Crawford HC, Lichtenthaler SF. Colombo A, et al. Among authors: lichtenthaler sf. Neurobiol Dis. 2013 Jan;49:137-47. doi: 10.1016/j.nbd.2012.08.011. Epub 2012 Aug 24. Neurobiol Dis. 2013. PMID: 22940630 Free PMC article.

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