Schaffer A - Search Results

1

Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements.

Schaffer A, Kim EC, Wu X, Zan H, Testoni L, Salamon S, Cerutti A, Casali P. Schaffer A, et al. J Biol Chem. 2003 Jun 20;278(25):23141-50. doi: 10.1074/jbc.M212952200. Epub 2003 Apr 2. J Biol Chem. 2003. PMID: 12672812 Free article.

2

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL.

Litinskiy MB, Nardelli B, Hilbert DM, He B, Schaffer A, Casali P, Cerutti A. Litinskiy MB, et al. Among authors: schaffer a. Nat Immunol. 2002 Sep;3(9):822-9. doi: 10.1038/ni829. Epub 2002 Aug 5. Nat Immunol. 2002. PMID: 12154359 Free PMC article.

3

Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells.

Cerutti A, Zan H, Kim EC, Shah S, Schattner EJ, Schaffer A, Casali P. Cerutti A, et al. Among authors: schaffer a. J Immunol. 2002 Dec 1;169(11):6594-603. doi: 10.4049/jimmunol.169.11.6594. J Immunol. 2002. PMID: 12444172 Free PMC article.

4

The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination.

Kim EC, Edmonston CR, Wu X, Schaffer A, Casali P. Kim EC, et al. Among authors: schaffer a. J Biol Chem. 2004 Oct 1;279(40):42258-69. doi: 10.1074/jbc.M407496200. Epub 2004 Jul 13. J Biol Chem. 2004. PMID: 15252056 Free PMC article.

5

CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal IgM+IgD+ B cell line.

Cerutti A, Zan H, Schaffer A, Bergsagel L, Harindranath N, Max EE, Casali P. Cerutti A, et al. Among authors: schaffer a. J Immunol. 1998 Mar 1;160(5):2145-57. J Immunol. 1998. PMID: 9498752 Free PMC article.

6

CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells.

Cerutti A, Schaffer A, Shah S, Zan H, Liou HC, Goodwin RG, Casali P. Cerutti A, et al. Among authors: schaffer a. Immunity. 1998 Aug;9(2):247-56. doi: 10.1016/s1074-7613(00)80607-x. Immunity. 1998. PMID: 9729045 Free PMC article.

7

CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-beta: evidence for TGF-beta but not IL-10-dependent direct S mu-->S alpha and sequential S mu-->S gamma, S gamma-->S alpha DNA recombination.

Zan H, Cerutti A, Dramitinos P, Schaffer A, Casali P. Zan H, et al. Among authors: schaffer a. J Immunol. 1998 Nov 15;161(10):5217-25. J Immunol. 1998. PMID: 9820493 Free PMC article.

8

Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation.

Zan H, Cerutti A, Dramitinos P, Schaffer A, Li Z, Casali P. Zan H, et al. Among authors: schaffer a. J Immunol. 1999 Mar 15;162(6):3437-47. J Immunol. 1999. PMID: 10092799 Free PMC article.

9

Engagement of CD153 (CD30 ligand) by CD30+ T cells inhibits class switch DNA recombination and antibody production in human IgD+ IgM+ B cells.

Cerutti A, Schaffer A, Goodwin RG, Shah S, Zan H, Ely S, Casali P. Cerutti A, et al. Among authors: schaffer a. J Immunol. 2000 Jul 15;165(2):786-94. doi: 10.4049/jimmunol.165.2.786. J Immunol. 2000. PMID: 10878352 Free PMC article.

10

Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells.

Cerutti A, Kim EC, Shah S, Schattner EJ, Zan H, Schaffer A, Casali P. Cerutti A, et al. Among authors: schaffer a. Nat Immunol. 2001 Feb;2(2):150-6. doi: 10.1038/84254. Nat Immunol. 2001. PMID: 11175813 Free PMC article.

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