Ojima I - Search Results

1

Second generation taxanes: from the natural framework to the challenge of drug resistance.

Ferlini C, Ojima I, Distefano M, Gallo D, Riva A, Morazzoni P, Bombardelli E, Mancuso S, Scambia G. Ferlini C, et al. Among authors: ojima i. Curr Med Chem Anticancer Agents. 2003 Mar;3(2):133-8. doi: 10.2174/1568011033353489. Curr Med Chem Anticancer Agents. 2003. PMID: 12678907 Review.

2

Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells.

Ojima I, Slater JC, Michaud E, Kuduk SD, Bounaud PY, Vrignaud P, Bissery MC, Veith JM, Pera P, Bernacki RJ. Ojima I, et al. J Med Chem. 1996 Sep 27;39(20):3889-96. doi: 10.1021/jm9604080. J Med Chem. 1996. PMID: 8831755

3

Anti-proliferative activity of a new class of taxanes (14beta-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells.

Distefano M, Scambia G, Ferlini C, Gaggini C, De Vincenzo R, Riva A, Bombardelli E, Ojima I, Fattorossi A, Panici PB, Mancuso S. Distefano M, et al. Among authors: ojima i. Int J Cancer. 1997 Sep 4;72(5):844-50. doi: 10.1002/(sici)1097-0215(19970904)72:5<844::aid-ijc22>3.0.co;2-7. Int J Cancer. 1997. PMID: 9311603

4

Cytotoxic effects toward human hematopoietic progenitor cells and tumor cell lines of paclitaxel, docetaxel, and newly developed analogues IDN5109, IDN5111, and IDN5127.

Ferlini C, Distefano M, Pierelli L, Bonanno G, Riva A, Bombardelli E, Ojima I, Mancuso S, Scambia G. Ferlini C, et al. Among authors: ojima i. Oncol Res. 1999;11(10):471-8. Oncol Res. 1999. PMID: 10850888

5

Syntheses and biological activity of C-3'-difluoromethyl-taxoids.

Ojima I, Lin S, Slater JC, Wang T, Pera P, Bernacki RJ, Ferlini C, Scambia G. Ojima I, et al. Bioorg Med Chem. 2000 Jul;8(7):1619-28. doi: 10.1016/s0968-0896(00)00093-6. Bioorg Med Chem. 2000. PMID: 10976509

6

Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors.

Ferlini C, Distefano M, Pignatelli F, Lin S, Riva A, Bombardelli E, Mancuso S, Ojima I, Scambia G. Ferlini C, et al. Among authors: ojima i. Br J Cancer. 2000 Dec;83(12):1762-8. doi: 10.1054/bjoc.2000.1500. Br J Cancer. 2000. PMID: 11104578 Free PMC article.

7

Effects of novel taxanes SB-T-1213 and IDN5109 on tubulin polymerization and mitosis.

Jordan MA, Ojima I, Rosas F, Distefano M, Wilson L, Scambia G, Ferlini C. Jordan MA, et al. Among authors: ojima i. Chem Biol. 2002 Jan;9(1):93-101. doi: 10.1016/s1074-5521(01)00097-7. Chem Biol. 2002. PMID: 11841942

8

New insights into drug resistance in cancer.

Ojima I, Ferlini C. Ojima I, et al. Chem Biol. 2003 Jul;10(7):583-4. doi: 10.1016/s1074-5521(03)00152-2. Chem Biol. 2003. PMID: 12890528 Free article.

9

Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III beta-tubulin.

Pepe A, Sun L, Zanardi I, Wu X, Ferlini C, Fontana G, Bombardelli E, Ojima I. Pepe A, et al. Among authors: ojima i. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3300-4. doi: 10.1016/j.bmcl.2009.04.070. Epub 2009 Apr 22. Bioorg Med Chem Lett. 2009. PMID: 19423340 Free PMC article.

10

Syntheses and structure-activity relationships of taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III.

Ojima I, Slater JC, Kuduk SD, Takeuchi CS, Gimi RH, Sun CM, Park YH, Pera P, Veith JM, Bernacki RJ. Ojima I, et al. J Med Chem. 1997 Jan 31;40(3):267-78. doi: 10.1021/jm960563e. J Med Chem. 1997. PMID: 9022793

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