Hausheer F - Search Results

1

Modulation of plasma thiols and mixed disulfides by BNP7787 in patients receiving paclitaxel/cisplatin therapy.

Pendyala L, Schwartz G, Smith P, Zdanowicz J, Murphy M, Hausheer F. Pendyala L, et al. Among authors: hausheer f. Cancer Chemother Pharmacol. 2003 May;51(5):376-84. doi: 10.1007/s00280-003-0587-y. Epub 2003 Apr 8. Cancer Chemother Pharmacol. 2003. PMID: 12682786

2

Pharmacokinetics of BNP7787 and its metabolite mesna in plasma and ascites: a case report.

Verschraagen M, Boven E, Zegers I, Hausheer FH, Van der Vijgh WJ. Verschraagen M, et al. Among authors: hausheer fh. Cancer Chemother Pharmacol. 2003 Jun;51(6):525-9. doi: 10.1007/s00280-003-0578-z. Epub 2003 May 15. Cancer Chemother Pharmacol. 2003. PMID: 12750838 Clinical Trial.

3

Phase I and pharmacologic study of BNP7787, a novel chemoprotector in patients with advanced non-small cell lung cancer.

Masuda N, Negoro S, Hausheer F, Nakagawa K, Matsui K, Kudoh S, Takeda K, Yamamoto N, Yoshimura N, Ohashi Y, Fukuoka M. Masuda N, et al. Among authors: hausheer f. Cancer Chemother Pharmacol. 2011 Mar;67(3):533-42. doi: 10.1007/s00280-010-1340-y. Epub 2010 May 15. Cancer Chemother Pharmacol. 2011. PMID: 20473611 Free PMC article. Clinical Trial.

4

Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of gamma-glutamyl transpeptidase.

Hausheer FH, Shanmugarajah D, Leverett BD, Chen X, Huang Q, Kochat H, Petluru PN, Parker AR. Hausheer FH, et al. Cancer Chemother Pharmacol. 2010 Apr;65(5):941-51. doi: 10.1007/s00280-009-1101-y. Epub 2009 Aug 28. Cancer Chemother Pharmacol. 2010. PMID: 19714332

5

The chemical reactivity of BNP7787 and its metabolite mesna with the cytostatic agent cisplatin: comparison with the nucleophiles thiosulfate, DDTC, glutathione and its disulfide GSSG.

Verschraagen M, Kedde MA, Hausheer FH, Van Der Vijgh WJ. Verschraagen M, et al. Among authors: hausheer fh. Cancer Chemother Pharmacol. 2003 Jun;51(6):499-504. doi: 10.1007/s00280-003-0610-3. Epub 2003 Apr 25. Cancer Chemother Pharmacol. 2003. PMID: 12715205

6

Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N.

Hausheer FH, Parker AR, Petluru PN, Jair KW, Chen S, Huang Q, Chen X, Ayala PY, Shanmugarajah D, Kochat H. Hausheer FH, et al. Cancer Chemother Pharmacol. 2011 Feb;67(2):381-91. doi: 10.1007/s00280-010-1333-x. Epub 2010 May 4. Cancer Chemother Pharmacol. 2011. PMID: 20440617

7

Possible (enzymatic) routes and biological sites for metabolic reduction of BNP7787, a new protector against cisplatin-induced side-effects.

Verschraagen M, Boven E, Torun E, Hausheer FH, Bast A, van der Vijgh WJ. Verschraagen M, et al. Among authors: hausheer fh. Biochem Pharmacol. 2004 Aug 1;68(3):493-502. doi: 10.1016/j.bcp.2004.04.005. Biochem Pharmacol. 2004. PMID: 15242815

8

Pharmacokinetics and preliminary clinical data of the novel chemoprotectant BNP7787 and cisplatin and their metabolites.

Verschraagen M, Boven E, Ruijter R, van der Born K, Berkhof J, Hausheer FH, van der Vijgh WJ. Verschraagen M, et al. Among authors: hausheer fh. Clin Pharmacol Ther. 2003 Aug;74(2):157-69. doi: 10.1016/S0009-9236(03)00150-4. Clin Pharmacol Ther. 2003. PMID: 12891226 Clinical Trial.

9

BNP7787-mediated modulation of paclitaxel- and cisplatin-induced aberrant microtubule protein polymerization in vitro.

Parker AR, Petluru PN, Wu M, Zhao M, Kochat H, Hausheer FH. Parker AR, et al. Among authors: hausheer fh. Mol Cancer Ther. 2010 Sep;9(9):2558-67. doi: 10.1158/1535-7163.MCT-10-0300. Epub 2010 Aug 31. Mol Cancer Ther. 2010. PMID: 20807779

10

Pharmacokinetic behaviour of the chemoprotectants BNP7787 and mesna after an i.v. bolus injection in rats.

Verschraagen M, Boven E, Torun E, Erkelens CA, Hausheer FH, van der Vijgh WJ. Verschraagen M, et al. Among authors: hausheer fh. Br J Cancer. 2004 Apr 19;90(8):1654-9. doi: 10.1038/sj.bjc.6601719. Br J Cancer. 2004. PMID: 15083199 Free PMC article.

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