Tenen DG - Search Results

1

Biallelic mutations in the CEBPA gene and low CEBPA expression levels as prognostic markers in intermediate-risk AML.

Barjesteh van Waalwijk van Doorn-Khosrovani S, Erpelinck C, Meijer J, van Oosterhoud S, van Putten WL, Valk PJ, Berna Beverloo H, Tenen DG, Löwenberg B, Delwel R. Barjesteh van Waalwijk van Doorn-Khosrovani S, et al. Among authors: tenen dg. Hematol J. 2003;4(1):31-40. doi: 10.1038/sj.thj.6200216. Hematol J. 2003. PMID: 12692518

2

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia.

Pabst T, Mueller BU, Zhang P, Radomska HS, Narravula S, Schnittger S, Behre G, Hiddemann W, Tenen DG. Pabst T, et al. Among authors: tenen dg. Nat Genet. 2001 Mar;27(3):263-70. doi: 10.1038/85820. Nat Genet. 2001. PMID: 11242107

3

Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.

Steidl U, Rosenbauer F, Verhaak RG, Gu X, Ebralidze A, Otu HH, Klippel S, Steidl C, Bruns I, Costa DB, Wagner K, Aivado M, Kobbe G, Valk PJ, Passegué E, Libermann TA, Delwel R, Tenen DG. Steidl U, et al. Among authors: tenen dg. Nat Genet. 2006 Nov;38(11):1269-77. doi: 10.1038/ng1898. Epub 2006 Oct 15. Nat Genet. 2006. PMID: 17041602

4

Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.

Wouters BJ, Jordà MA, Keeshan K, Louwers I, Erpelinck-Verschueren CA, Tielemans D, Langerak AW, He Y, Yashiro-Ohtani Y, Zhang P, Hetherington CJ, Verhaak RG, Valk PJ, Löwenberg B, Tenen DG, Pear WS, Delwel R. Wouters BJ, et al. Among authors: tenen dg. Blood. 2007 Nov 15;110(10):3706-14. doi: 10.1182/blood-2007-02-073486. Epub 2007 Aug 1. Blood. 2007. PMID: 17671232 Free PMC article.

5

A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.

Steidl U, Steidl C, Ebralidze A, Chapuy B, Han HJ, Will B, Rosenbauer F, Becker A, Wagner K, Koschmieder S, Kobayashi S, Costa DB, Schulz T, O'Brien KB, Verhaak RG, Delwel R, Haase D, Trümper L, Krauter J, Kohwi-Shigematsu T, Griesinger F, Tenen DG. Steidl U, et al. Among authors: tenen dg. J Clin Invest. 2007 Sep;117(9):2611-20. doi: 10.1172/JCI30525. J Clin Invest. 2007. PMID: 17694175 Free PMC article.

6

Gene transactivation without direct DNA binding defines a novel gain-of-function for PML-RARalpha.

van Wageningen S, Breems-de Ridder MC, Nigten J, Nikoloski G, Erpelinck-Verschueren CA, Löwenberg B, de Witte T, Tenen DG, van der Reijden BA, Jansen JH. van Wageningen S, et al. Among authors: tenen dg. Blood. 2008 Feb 1;111(3):1634-43. doi: 10.1182/blood-2007-04-081125. Epub 2007 Nov 19. Blood. 2008. PMID: 18025157 Free article.

7

C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations.

Pulikkan JA, Peramangalam PS, Dengler V, Ho PA, Preudhomme C, Meshinchi S, Christopeit M, Nibourel O, Müller-Tidow C, Bohlander SK, Tenen DG, Behre G. Pulikkan JA, et al. Among authors: tenen dg. Blood. 2010 Dec 16;116(25):5638-49. doi: 10.1182/blood-2010-04-281600. Epub 2010 Oct 1. Blood. 2010. PMID: 20889924 Free PMC article.

8

Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα.

Radomska HS, Alberich-Jordà M, Will B, Gonzalez D, Delwel R, Tenen DG. Radomska HS, et al. Among authors: tenen dg. J Clin Invest. 2012 Aug;122(8):2955-66. doi: 10.1172/JCI43354. Epub 2012 Jul 17. J Clin Invest. 2012. PMID: 22797303 Free PMC article.

9

C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.

Alberich-Jordà M, Wouters B, Balastik M, Shapiro-Koss C, Zhang H, Di Ruscio A, Radomska HS, Ebralidze AK, Amabile G, Ye M, Zhang J, Lowers I, Avellino R, Melnick A, Figueroa ME, Valk PJ, Delwel R, Tenen DG. Alberich-Jordà M, et al. Among authors: tenen dg. J Clin Invest. 2012 Dec;122(12):4490-504. doi: 10.1172/JCI65102. Epub 2012 Nov 19. J Clin Invest. 2012. PMID: 23160200 Free PMC article.

10

The gene signature in CCAAT-enhancer-binding protein α dysfunctional acute myeloid leukemia predicts responsiveness to histone deacetylase inhibitors.

Liss A, Ooi CH, Zjablovskaja P, Benoukraf T, Radomska HS, Ju C, Wu M, Balastik M, Delwel R, Brdicka T, Tan P, Tenen DG, Alberich-Jorda M. Liss A, et al. Among authors: tenen dg. Haematologica. 2014 Apr;99(4):697-705. doi: 10.3324/haematol.2013.093278. Epub 2013 Oct 25. Haematologica. 2014. PMID: 24162792 Free PMC article.

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