Ozawa S - Search Results

1

Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10.

Jinno H, Saeki M, Tanaka-Kagawa T, Hanioka N, Saito Y, Ozawa S, Ando M, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Sawada J. Jinno H, et al. Among authors: ozawa s. Drug Metab Dispos. 2003 May;31(5):528-32. doi: 10.1124/dmd.31.5.528. Drug Metab Dispos. 2003. PMID: 12695339

2

Interaction of irinotecan (CPT-11) and its active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38) with human cytochrome P450 enzymes.

Hanioka N, Ozawa S, Jinno H, Tanaka-Kagawa T, Nishimura T, Ando M, Sawada Ji J. Hanioka N, et al. Among authors: ozawa s. Drug Metab Dispos. 2002 Apr;30(4):391-6. doi: 10.1124/dmd.30.4.391. Drug Metab Dispos. 2002. PMID: 11901092

3

Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D.

Jinno H, Tanaka-Kagawa T, Hanioka N, Saeki M, Ishida S, Nishimura T, Ando M, Saito Y, Ozawa S, Sawada J. Jinno H, et al. Among authors: ozawa s. Drug Metab Dispos. 2003 Jan;31(1):108-13. doi: 10.1124/dmd.31.1.108. Drug Metab Dispos. 2003. PMID: 12485959

4

Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients.

Jinno H, Saeki M, Saito Y, Tanaka-Kagawa T, Hanioka N, Sai K, Kaniwa N, Ando M, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Ozawa S, Sawada J. Jinno H, et al. Among authors: ozawa s. J Pharmacol Exp Ther. 2003 Aug;306(2):688-93. doi: 10.1124/jpet.103.051250. Epub 2003 May 1. J Pharmacol Exp Ther. 2003. PMID: 12730278

5

Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region.

Koyano S, Kurose K, Saito Y, Ozawa S, Hasegawa R, Komamura K, Ueno K, Kamakura S, Kitakaze M, Nakajima T, Matsumoto K, Akasawa A, Saito H, Sawada J. Koyano S, et al. Among authors: ozawa s. Drug Metab Dispos. 2004 Jan;32(1):149-54. doi: 10.1124/dmd.32.1.149. Drug Metab Dispos. 2004. PMID: 14709632

6

Involvement of human hepatic UGT1A1, UGT2B4, and UGT2B7 in the glucuronidation of carvedilol.

Ohno A, Saito Y, Hanioka N, Jinno H, Saeki M, Ando M, Ozawa S, Sawada J. Ohno A, et al. Among authors: ozawa s. Drug Metab Dispos. 2004 Feb;32(2):235-9. doi: 10.1124/dmd.32.2.235. Drug Metab Dispos. 2004. PMID: 14744946

7

Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.

Saeki M, Saito Y, Jinno H, Tanaka-Kagawa T, Ohno A, Ozawa S, Ueno K, Kamakura S, Kamatani N, Komamura K, Kitakaze M, Sawada J. Saeki M, et al. Among authors: ozawa s. Drug Metab Dispos. 2004 Sep;32(9):1048-54. Drug Metab Dispos. 2004. PMID: 15319348

8

Functional characterization of five novel CYP2C8 variants, G171S, R186X, R186G, K247R, and K383N, found in a Japanese population.

Hichiya H, Tanaka-Kagawa T, Soyama A, Jinno H, Koyano S, Katori N, Matsushima E, Uchiyama S, Tokunaga H, Kimura H, Minami N, Katoh M, Sugai K, Goto Y, Tamura T, Yamamoto N, Ohe Y, Kunitoh H, Nokihara H, Yoshida T, Minami H, Saijo N, Ando M, Ozawa S, Saito Y, Sawada J. Hichiya H, et al. Among authors: ozawa s. Drug Metab Dispos. 2005 May;33(5):630-6. doi: 10.1124/dmd.105.003830. Epub 2005 Feb 16. Drug Metab Dispos. 2005. PMID: 15716363

9

Functional analysis of six human aryl hydrocarbon receptor variants in a Japanese population.

Koyano S, Saito Y, Fukushima-Uesaka H, Ishida S, Ozawa S, Kamatani N, Minami H, Ohtsu A, Hamaguchi T, Shirao K, Yoshida T, Saijo N, Jinno H, Sawada J. Koyano S, et al. Among authors: ozawa s. Drug Metab Dispos. 2005 Aug;33(8):1254-60. doi: 10.1124/dmd.105.004655. Epub 2005 Apr 28. Drug Metab Dispos. 2005. PMID: 15860653

10

Functional characterization of three naturally occurring single nucleotide polymorphisms in the CES2 gene encoding carboxylesterase 2 (HCE-2).

Kubo T, Kim SR, Sai K, Saito Y, Nakajima T, Matsumoto K, Saito H, Shirao K, Yamamoto N, Minami H, Ohtsu A, Yoshida T, Saijo N, Ohno Y, Ozawa S, Sawada J. Kubo T, et al. Among authors: ozawa s. Drug Metab Dispos. 2005 Oct;33(10):1482-7. doi: 10.1124/dmd.105.005587. Epub 2005 Jul 20. Drug Metab Dispos. 2005. PMID: 16033949

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