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A new selective estrogen receptor modulator with potent uterine antagonist activity, agonist activity in bone, and minimal ovarian stimulation.
Geiser AG, Hummel CW, Draper MW, Henck JW, Cohen IR, Rudmann DG, Donnelly KB, Adrian MD, Shepherd TA, Wallace OB, McCann DJ, Oldham SW, Bryant HU, Sato M, Dodge JA. Geiser AG, et al. Among authors: sato m. Endocrinology. 2005 Oct;146(10):4524-35. doi: 10.1210/en.2005-0024. Epub 2005 Jul 7. Endocrinology. 2005. PMID: 16002528
Expression profiling of rat femur revealed suppression of bone formation genes by treatment with alendronate and estrogen but not raloxifene.
Helvering LM, Liu R, Kulkarni NH, Wei T, Chen P, Huang S, Lawrence F, Halladay DL, Miles RR, Ambrose EM, Sato M, Ma YL, Frolik CA, Dow ER, Bryant HU, Onyia JE. Helvering LM, et al. Among authors: sato m. Mol Pharmacol. 2005 Nov;68(5):1225-38. doi: 10.1124/mol.105.011478. Epub 2005 Aug 3. Mol Pharmacol. 2005. PMID: 16079270
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