Choi Y - Search Results

1

Differential binding modes of diacylglycerol (DAG) and DAG lactones to protein kinase C (PK-C).

Sigano DM, Peach ML, Nacro K, Choi Y, Lewin NE, Nicklaus MC, Blumberg PM, Marquez VE. Sigano DM, et al. Among authors: choi y. J Med Chem. 2003 Apr 24;46(9):1571-9. doi: 10.1021/jm020476o. J Med Chem. 2003. PMID: 12699375

2

Conformationally constrained analogues of diacylglycerol. 19. Synthesis and protein kinase C binding affinity of diacylglycerol lactones bearing an N-hydroxylamide side chain.

Choi Y, Kang JH, Lewin NE, Blumberg PM, Lee J, Marquez VE. Choi Y, et al. J Med Chem. 2003 Jun 19;46(13):2790-3. doi: 10.1021/jm030082c. J Med Chem. 2003. PMID: 12801241

3

Conformationally constrained analogues of diacylglycerol (DAG). 28. DAG-dioxolanones reveal a new additional interaction site in the C1b domain of PKC delta.

Choi Y, Pu Y, Peach ML, Kang JH, Lewin NE, Sigano DM, Garfield SH, Blumberg PM, Marquez VE. Choi Y, et al. J Med Chem. 2007 Jul 26;50(15):3465-81. doi: 10.1021/jm0702579. Epub 2007 Jun 26. J Med Chem. 2007. PMID: 17591763

4

Enantioselective synthesis of bicyclo[3.1.0]hexane carbocyclic nucleosides via a lipase-catalyzed asymmetric acetylation. Characterization of an unusual acetal byproduct.

Yoshimura Y, Moon HR, Choi Y, Marquez VE. Yoshimura Y, et al. Among authors: choi y. J Org Chem. 2002 Aug 23;67(17):5938-45. doi: 10.1021/jo020249u. J Org Chem. 2002. PMID: 12182625

5

A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude.

Choi Y, George C, Comin MJ, Barchi JJ Jr, Kim HS, Jacobson KA, Balzarini J, Mitsuya H, Boyer PL, Hughes SH, Marquez VE. Choi Y, et al. J Med Chem. 2003 Jul 17;46(15):3292-9. doi: 10.1021/jm030116g. J Med Chem. 2003. PMID: 12852759

6

Recent advances in the synthesis of conformationally locked nucleosides and their success in probing the critical question of conformational preferences by their biological targets.

Choi Y, Moon HR, Yoshimura Y, Marquez VE. Choi Y, et al. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):547-57. doi: 10.1081/NCN-120021954. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565229 Review.

7

2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists.

Kim HS, Ohno M, Xu B, Kim HO, Choi Y, Ji XD, Maddileti S, Marquez VE, Harden TK, Jacobson KA. Kim HS, et al. Among authors: choi y. J Med Chem. 2003 Nov 6;46(23):4974-87. doi: 10.1021/jm030127+. J Med Chem. 2003. PMID: 14584948 Free PMC article.

8

Synthesis and conformational analysis of a locked analogue of carbovir built on a bicyclo[3.1.0]hex-2-enyl template.

Choi Y, Sun G, George C, Nicklaus MC, Kelley JA, Marquez VE. Choi Y, et al. Nucleosides Nucleotides Nucleic Acids. 2003 Dec;22(12):2077-91. doi: 10.1081/ncn-120026631. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14714758

9

Synthesis of a conformationally locked version of puromycin amino nucleoside.

Choi Y, George C, Strazewski P, Marquez VE. Choi Y, et al. Org Lett. 2002 Feb 21;4(4):589-92. doi: 10.1021/ol010288c. Org Lett. 2002. PMID: 11843598

10

Synthesis of conformationally locked versions of puromycin analogues.

Saneyoshi H, Michel BY, Choi Y, Strazewski P, Marquez VE. Saneyoshi H, et al. Among authors: choi y. J Org Chem. 2008 Dec 5;73(23):9435-8. doi: 10.1021/jo8016132. J Org Chem. 2008. PMID: 18991379 Free PMC article.

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