Singh SV - Search Results

1

JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity.

Shami PJ, Saavedra JE, Wang LY, Bonifant CL, Diwan BA, Singh SV, Gu Y, Fox SD, Buzard GS, Citro ML, Waterhouse DJ, Davies KM, Ji X, Keefer LK. Shami PJ, et al. Among authors: singh sv. Mol Cancer Ther. 2003 Apr;2(4):409-17. Mol Cancer Ther. 2003. PMID: 12700285

2

Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer.

Singh KB, Ji X, Singh SV. Singh KB, et al. Among authors: singh sv. Mol Cancer Ther. 2018 Oct;17(10):2079-2090. doi: 10.1158/1535-7163.MCT-18-0117. Epub 2018 Jul 20. Mol Cancer Ther. 2018. PMID: 30030299 Free PMC article.

3

Structure-Based Design of Anticancer Prodrug PABA/NO.

Ji X, Pal A, Kalathur R, Hu X, Gu Y, Saavedra JE, Buzard GS, Srinivasan A, Keefer LK, Singh SV. Ji X, et al. Among authors: singh sv. Drug Des Devel Ther. 2008;2:123-130. doi: 10.2147/dddt.s3931. Drug Des Devel Ther. 2008. PMID: 19662104 Free PMC article.

4

Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity.

Gu Y, Guo J, Pal A, Pan SS, Zimniak P, Singh SV, Ji X. Gu Y, et al. Among authors: singh sv. Biochemistry. 2004 Dec 21;43(50):15673-9. doi: 10.1021/bi048757g. Biochemistry. 2004. PMID: 15595823

5

Residues 207, 216, and 221 and the catalytic activity of mGSTA1-1 and mGSTA2-2 toward benzo[a]pyrene-(7R,8S)-diol-(9S,10R)-epoxide.

Gu Y, Xiao B, Wargo HL, Bucher MH, Singh SV, Ji X. Gu Y, et al. Among authors: singh sv. Biochemistry. 2003 Feb 4;42(4):917-21. doi: 10.1021/bi026778+. Biochemistry. 2003. PMID: 12549910

6

Structural basis for catalytic differences between alpha class human glutathione transferases hGSTA1-1 and hGSTA2-2 for glutathione conjugation of environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide.

Singh SV, Varma V, Zimniak P, Srivastava SK, Marynowski SW, Desai D, Amin S, Ji X. Singh SV, et al. Biochemistry. 2004 Aug 3;43(30):9708-15. doi: 10.1021/bi049435f. Biochemistry. 2004. PMID: 15274625

7

Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak.

Singh SV, Zeng Y, Xiao D, Vogel VG, Nelson JB, Dhir R, Tripathi YB. Singh SV, et al. Mol Cancer Ther. 2005 Nov;4(11):1747-54. doi: 10.1158/1535-7163.MCT-05-0223. Mol Cancer Ther. 2005. PMID: 16275996

8

Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical.

Kumari V, Dyba MA, Holland RJ, Liang YH, Singh SV, Ji X. Kumari V, et al. Among authors: singh sv. PLoS One. 2016 Sep 29;11(9):e0163821. doi: 10.1371/journal.pone.0163821. eCollection 2016. PLoS One. 2016. PMID: 27684484 Free PMC article.

9

Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak.

Xiao D, Vogel V, Singh SV. Xiao D, et al. Among authors: singh sv. Mol Cancer Ther. 2006 Nov;5(11):2931-45. doi: 10.1158/1535-7163.MCT-06-0396. Mol Cancer Ther. 2006. PMID: 17121941

10

Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.

Xiao D, Johnson CS, Trump DL, Singh SV. Xiao D, et al. Among authors: singh sv. Mol Cancer Ther. 2004 May;3(5):567-75. Mol Cancer Ther. 2004. PMID: 15141014

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