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Page 1
Tracking non-genetic evolution from primary to metastatic ccRCC: TRACERx Renal.
Fernández-Sanromán Á, Fendler A, Tan BJY, Cattin AL, Spencer C, Thompson R, Au L, Lobon I, Pallikonda HA, Martin A, Byrne F, Franz A, Mikolajczak A, Rahman H, Tippu Z, Shepherd STC, Feng H, Deng D, Rowan A, Pickering L, Furness AJS, Young K, Nicol D, Rudman SM, O'Brien T, Edmonds K, Chandra A, Hazell S, Litchfield K, Kassiotis G, Larkin J, Turajlic S. Fernández-Sanromán Á, et al. Among authors: shepherd stc. Cancer Discov. 2025 Jan 8. doi: 10.1158/2159-8290.CD-24-0499. Online ahead of print. Cancer Discov. 2025. PMID: 39774619
Solution biophysics identifies lipid nanoparticle non-sphericity, polydispersity, and dependence on internal ordering for efficacious mRNA delivery.
Padilla MS, Shepherd SJ, Hanna AR, Kurnik M, Zhang X, Chen M, Byrnes J, Yamagata HM, Ricciardi A, Joseph RA, Mrksich K, Issadore D, Gupta K, Mitchell MJ. Padilla MS, et al. Among authors: shepherd sj. bioRxiv [Preprint]. 2024 Dec 22:2024.12.19.629496. doi: 10.1101/2024.12.19.629496. bioRxiv. 2024. PMID: 39763759 Free PMC article. Preprint.
Pharmacological and structural understanding of the Trypanosoma cruzi proteasome provides key insights for developing site-specific inhibitors.
Eadsforth TC, Torrie LS, Rowland P, Edgar EV, MacLean LM, Paterson C, Robinson DA, Shepherd SM, Thomas J, Thomas MG, Gray DW, Postis VLG, De Rycker M. Eadsforth TC, et al. Among authors: shepherd sm. J Biol Chem. 2024 Dec 9;301(1):108049. doi: 10.1016/j.jbc.2024.108049. Online ahead of print. J Biol Chem. 2024. PMID: 39638245 Free article.
Early childhood body mass index growth and school readiness: A longitudinal cohort study.
Li X, Kahane A, Keown-Stoneman CDG, Omand JA, Borkhoff CM, Lebovic G, Maguire JL, Mamdani M, Parkin PC, Simpson JR, Tremblay MS, Vanderloo LM, Duku E, Reid-Westoby C, Janus M, Birken CS; TARGet Kids! Collaboration. Li X, et al. Paediatr Perinat Epidemiol. 2024 Nov;38(8):733-744. doi: 10.1111/ppe.13114. Paediatr Perinat Epidemiol. 2024. PMID: 39607066
Bioinspired designer DNA NanoGripper for virus sensing and potential inhibition.
Zhou L, Xiong Y, Dwivedy A, Zheng M, Cooper L, Shepherd S, Song T, Hong W, Le LTP, Chen X, Umrao S, Rong L, Wang T, Cunningham BT, Wang X. Zhou L, et al. Among authors: shepherd s. Sci Robot. 2024 Nov 27;9(96):eadi2084. doi: 10.1126/scirobotics.adi2084. Epub 2024 Nov 27. Sci Robot. 2024. PMID: 39602515
Intravenous glibenclamide for cerebral oedema after large hemispheric stroke (CHARM): a phase 3, double-blind, placebo-controlled, randomised trial.
Sheth KN, Albers GW, Saver JL, Campbell BCV, Molyneaux BJ, Hinson HE, Cordonnier C, Steiner T, Toyoda K, Wintermark M, Littauer R, Collins J, Lucas N, Nogueira RG, Simard JM, Wald M, Dawson K, Kimberly WT; CHARM Trial investigators. Sheth KN, et al. Lancet Neurol. 2024 Dec;23(12):1205-1213. doi: 10.1016/S1474-4422(24)00425-3. Lancet Neurol. 2024. PMID: 39577921 Clinical Trial.
950 results