Lobb RR - Search Results

1

Obtustatin: a potent selective inhibitor of alpha1beta1 integrin in vitro and angiogenesis in vivo.

Marcinkiewicz C, Weinreb PH, Calvete JJ, Kisiel DG, Mousa SA, Tuszynski GP, Lobb RR. Marcinkiewicz C, et al. Among authors: lobb rr. Cancer Res. 2003 May 1;63(9):2020-3. Cancer Res. 2003. PMID: 12727812

2

Isolation and characterization of EMS16, a C-lectin type protein from Echis multisquamatus venom, a potent and selective inhibitor of the alpha2beta1 integrin.

Marcinkiewicz C, Lobb RR, Marcinkiewicz MM, Daniel JL, Smith JB, Dangelmaier C, Weinreb PH, Beacham DA, Niewiarowski S. Marcinkiewicz C, et al. Among authors: lobb rr. Biochemistry. 2000 Aug 15;39(32):9859-67. doi: 10.1021/bi000428a. Biochemistry. 2000. PMID: 10933804

3

EC3, a novel heterodimeric disintegrin from Echis carinatus venom, inhibits alpha4 and alpha5 integrins in an RGD-independent manner.

Marcinkiewicz C, Calvete JJ, Marcinkiewicz MM, Raida M, Vijay-Kumar S, Huang Z, Lobb RR, Niewiarowski S. Marcinkiewicz C, et al. Among authors: lobb rr. J Biol Chem. 1999 Apr 30;274(18):12468-73. doi: 10.1074/jbc.274.18.12468. J Biol Chem. 1999. PMID: 10212222 Free article.

4

Structural and functional characterization of EMF10, a heterodimeric disintegrin from Eristocophis macmahoni venom that selectively inhibits alpha 5 beta 1 integrin.

Marcinkiewicz C, Calvete JJ, Vijay-Kumar S, Marcinkiewicz MM, Raida M, Schick P, Lobb RR, Niewiarowski S. Marcinkiewicz C, et al. Among authors: lobb rr. Biochemistry. 1999 Oct 5;38(40):13302-9. doi: 10.1021/bi9906930. Biochemistry. 1999. PMID: 10529205

5

Inhibitory effects of MLDG-containing heterodimeric disintegrins reveal distinct structural requirements for interaction of the integrin alpha 9beta 1 with VCAM-1, tenascin-C, and osteopontin.

Marcinkiewicz C, Taooka Y, Yokosaki Y, Calvete JJ, Marcinkiewicz MM, Lobb RR, Niewiarowski S, Sheppard D. Marcinkiewicz C, et al. Among authors: lobb rr. J Biol Chem. 2000 Oct 13;275(41):31930-7. doi: 10.1074/jbc.M003209200. J Biol Chem. 2000. PMID: 10926928 Free article.

6

A cell-free electrochemiluminescence assay for measuring beta1-integrin-ligand interactions.

Weinreb PH, Yang WJ, Violette SM, Couture M, Kimball K, Pepinsky RB, Lobb RR, Josiah S. Weinreb PH, et al. Among authors: lobb rr. Anal Biochem. 2002 Jul 15;306(2):305-13. doi: 10.1006/abio.2002.5723. Anal Biochem. 2002. PMID: 12123670

7

Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.

Hahm K, Lukashev ME, Luo Y, Yang WJ, Dolinski BM, Weinreb PH, Simon KJ, Chun Wang L, Leone DR, Lobb RR, McCrann DJ, Allaire NE, Horan GS, Fogo A, Kalluri R, Shield CF 3rd, Sheppard D, Gardner HA, Violette SM. Hahm K, et al. Among authors: lobb rr. Am J Pathol. 2007 Jan;170(1):110-25. doi: 10.2353/ajpath.2007.060158. Am J Pathol. 2007. PMID: 17200187 Free PMC article.

8

Identification of ligand binding sites on integrin alpha4beta1 through chemical cross-linking.

Chen LL, Lobb RR, Cuervo JH, Lin Kc, Adams SP, Pepinsky RB. Chen LL, et al. Among authors: lobb rr. Biochemistry. 1998 Jun 16;37(24):8743-53. doi: 10.1021/bi980311a. Biochemistry. 1998. PMID: 9628736

9

Multiple activation states of integrin alpha4beta1 detected through their different affinities for a small molecule ligand.

Chen LL, Whitty A, Lobb RR, Adams SP, Pepinsky RB. Chen LL, et al. Among authors: lobb rr. J Biol Chem. 1999 May 7;274(19):13167-75. doi: 10.1074/jbc.274.19.13167. J Biol Chem. 1999. PMID: 10224072 Free article.

10

Comparative assessment of the ligand and metal ion binding properties of integrins alpha9beta1 and alpha4beta1.

Pepinsky RB, Mumford RA, Chen LL, Leone D, Amo SE, Riper GV, Whitty A, Dolinski B, Lobb RR, Dean DC, Chang LL, Raab CE, Si Q, Hagmann WK, Lingham RB. Pepinsky RB, et al. Among authors: lobb rr. Biochemistry. 2002 Jun 4;41(22):7125-41. doi: 10.1021/bi020024d. Biochemistry. 2002. PMID: 12033947

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