JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3.
Sunayama J, Tsuruta F, Masuyama N, Gotoh Y.
Sunayama J, et al. Among authors: masuyama n.
J Cell Biol. 2005 Jul 18;170(2):295-304. doi: 10.1083/jcb.200409117. Epub 2005 Jul 11.
J Cell Biol. 2005.
PMID: 16009721
Free PMC article.
Hattori, S. Shimizu, Y. Tsujimoto, K. Yoshioka, N. Masuyama, and Y. Gotoh. 2004. EMBO J. 23:1889-1899). Here, we show that phosphorylation of 14-3-3 by JNK releases the proapoptotic proteins Bad and FOXO3a from 14-3-3 and antagonizes the effects of Akt signaling. .. …
Hattori, S. Shimizu, Y. Tsujimoto, K. Yoshioka, N. Masuyama, and Y. Gotoh. 2004. EMBO J. 23:1889-1899). Here, we show that pho …