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RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1.
Kim DW, Hwang JH, Suh JM, Kim H, Song JH, Hwang ES, Hwang IY, Park KC, Chung HK, Kim JM, Park J, Hemmings BA, Shong M. Kim DW, et al. Among authors: hemmings ba. Mol Endocrinol. 2003 Jul;17(7):1382-94. doi: 10.1210/me.2002-0402. Epub 2003 May 8. Mol Endocrinol. 2003. PMID: 12738763
Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding.
Yang KJ, Shin S, Piao L, Shin E, Li Y, Park KA, Byun HS, Won M, Hong J, Kweon GR, Hur GM, Seok JH, Chun T, Brazil DP, Hemmings BA, Park J. Yang KJ, et al. Among authors: hemmings ba. J Biol Chem. 2008 Jan 18;283(3):1480-1491. doi: 10.1074/jbc.M706361200. Epub 2007 Nov 16. J Biol Chem. 2008. PMID: 18024423 Free article.
PKB binding proteins. Getting in on the Akt.
Brazil DP, Park J, Hemmings BA. Brazil DP, et al. Among authors: hemmings ba. Cell. 2002 Nov 1;111(3):293-303. doi: 10.1016/s0092-8674(02)01083-8. Cell. 2002. PMID: 12419241 Free article. Review.
322 results