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Tonabersat enhances temozolomide-mediated cytotoxicity in glioblastoma by disrupting intercellular connectivity through connexin 43 inhibition.
Schmidt ENC, Evert BO, Pregler BEF, Melhem A, Hsieh MC, Raspe M, Strobel H, Roos J, Pietsch T, Schuss P, Fischer-Posovszky P, Westhoff MA, Hölzel M, Herrlinger U, Vatter H, Waha A, Schneider M, Potthoff AL. Schmidt ENC, et al. Among authors: strobel h. Mol Oncol. 2024 Dec 16. doi: 10.1002/1878-0261.13786. Online ahead of print. Mol Oncol. 2024. PMID: 39680504 Free article.
Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma.
Freitag T, Kaps P, Ramtke J, Bertels S, Zunke E, Schneider B, Becker AS, Koczan D, Dubinski D, Freiman TM, Wittig F, Hinz B, Westhoff MA, Strobel H, Meiners F, Wolter D, Engel N, Troschke-Meurer S, Bergmann-Ewert W, Staehlke S, Wolff A, Gessler F, Junghanss C, Maletzki C. Freitag T, et al. Among authors: strobel h. NPJ Precis Oncol. 2024 Jul 25;8(1):156. doi: 10.1038/s41698-024-00653-3. NPJ Precis Oncol. 2024. PMID: 39054369 Free PMC article.
More evolvable bacteriophages better suppress their host.
Horwitz EK, Strobel HM, Haiso J, Meyer JR. Horwitz EK, et al. Among authors: strobel hm. Evol Appl. 2024 Jul 4;17(7):e13742. doi: 10.1111/eva.13742. eCollection 2024 Jul. Evol Appl. 2024. PMID: 38975285 Free PMC article.
Trauma-associated extracellular histones mediate inflammation via a MYD88-IRAK1-ERK signaling axis and induce lytic cell death in human adipocytes.
Roos J, Zinngrebe J, Huber-Lang M, Lupu L, Schmidt MA, Strobel H, Westhoff MA, Stifel U, Gebhard F, Wabitsch M, Mollnes TE, Debatin KM, Halbgebauer R, Fischer-Posovszky P. Roos J, et al. Among authors: strobel h. Cell Death Dis. 2024 Apr 23;15(4):285. doi: 10.1038/s41419-024-06676-9. Cell Death Dis. 2024. PMID: 38653969 Free PMC article.
Tumor Treating Fields (TTFields) combined with the drug repurposing approach CUSP9v3 induce metabolic reprogramming and synergistic anti-glioblastoma activity in vitro.
Cao Q, Hajosch A, Kast RE, Loehmann C, Hlavac M, Fischer-Posovszky P, Strobel H, Westhoff MA, Siegelin MD, Wirtz CR, Halatsch ME, Karpel-Massler G. Cao Q, et al. Among authors: strobel h. Br J Cancer. 2024 May;130(8):1365-1376. doi: 10.1038/s41416-024-02608-8. Epub 2024 Feb 23. Br J Cancer. 2024. PMID: 38396172 Free PMC article.
309 results