Winiwarter S - Search Results

1

Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-Length NS3 (protease-helicase/NTPase): a comparative study of different C-terminals.

Johansson A, Poliakov A, Akerblom E, Wiklund K, Lindeberg G, Winiwarter S, Danielson UH, Samuelsson B, Hallberg A. Johansson A, et al. Among authors: winiwarter s. Bioorg Med Chem. 2003 Jun 12;11(12):2551-68. doi: 10.1016/s0968-0896(03)00179-2. Bioorg Med Chem. 2003. PMID: 12757723

2

Tetrapeptides as potent protease inhibitors of Hepatitis C Virus full-length NS3 (protease-helicase/NTPase).

Johansson A, Poliakov A, Akerblom E, Lindeberg G, Winiwarter S, Samuelsson B, Danielson UH, Hallberg A. Johansson A, et al. Among authors: winiwarter s. Bioorg Med Chem. 2002 Dec;10(12):3915-22. doi: 10.1016/s0968-0896(02)00310-3. Bioorg Med Chem. 2002. PMID: 12413843

3

Inhibition of hepatitis C virus NS3 protease activity by product-based peptides is dependent on helicase domain.

Johansson A, Hubatsch I, Akerblom E, Lindeberg G, Winiwarter S, Danielson UH, Hallberg A. Johansson A, et al. Among authors: winiwarter s. Bioorg Med Chem Lett. 2001 Jan 22;11(2):203-6. doi: 10.1016/s0960-894x(00)00625-9. Bioorg Med Chem Lett. 2001. PMID: 11206459

4

Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach.

Winiwarter S, Bonham NM, Ax F, Hallberg A, Lennernäs H, Karlén A. Winiwarter S, et al. J Med Chem. 1998 Dec 3;41(25):4939-49. doi: 10.1021/jm9810102. J Med Chem. 1998. PMID: 9836611

5

Presentation of a structurally diverse and commercially available drug data set for correlation and benchmarking studies.

Sköld C, Winiwarter S, Wernevik J, Bergström F, Engström L, Allen R, Box K, Comer J, Mole J, Hallberg A, Lennernäs H, Lundstedt T, Ungell AL, Karlén A. Sköld C, et al. Among authors: winiwarter s. J Med Chem. 2006 Nov 16;49(23):6660-71. doi: 10.1021/jm0506219. J Med Chem. 2006. PMID: 17154497

6

Hydrogen bonding descriptors in the prediction of human in vivo intestinal permeability.

Winiwarter S, Ax F, Lennernäs H, Hallberg A, Pettersson C, Karlén A. Winiwarter S, et al. J Mol Graph Model. 2003 Jan;21(4):273-87. doi: 10.1016/s1093-3263(02)00163-8. J Mol Graph Model. 2003. PMID: 12479927

7

SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.

Danelian E, Karlén A, Karlsson R, Winiwarter S, Hansson A, Löfâs S, Lennernäs H, Hämäläinen MD. Danelian E, et al. Among authors: winiwarter s. J Med Chem. 2000 Jun 1;43(11):2083-6. doi: 10.1021/jm991156g. J Med Chem. 2000. PMID: 10841786 No abstract available.

8

Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.

Fridén M, Winiwarter S, Jerndal G, Bengtsson O, Wan H, Bredberg U, Hammarlund-Udenaes M, Antonsson M. Fridén M, et al. Among authors: winiwarter s. J Med Chem. 2009 Oct 22;52(20):6233-43. doi: 10.1021/jm901036q. J Med Chem. 2009. PMID: 19764786

9

In Silico Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics (ADME-PK): Utility and Best Practices. An Industry Perspective from the International Consortium for Innovation through Quality in Pharmaceutical Development.

Lombardo F, Desai PV, Arimoto R, Desino KE, Fischer H, Keefer CE, Petersson C, Winiwarter S, Broccatelli F. Lombardo F, et al. Among authors: winiwarter s. J Med Chem. 2017 Nov 22;60(22):9097-9113. doi: 10.1021/acs.jmedchem.7b00487. Epub 2017 Jun 27. J Med Chem. 2017. PMID: 28609624 Review.

10

Synthesis and structure-activity relationships of deazaxanthines: analogs of potent A1- and A2-adenosine receptor antagonists.

Grahner B, Winiwarter S, Lanzner W, Müller CE. Grahner B, et al. Among authors: winiwarter s. J Med Chem. 1994 May 13;37(10):1526-34. doi: 10.1021/jm00036a019. J Med Chem. 1994. PMID: 8182711

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