Shigematsu K - Search Results

1

Deletion of N-terminal residues 23-88 from prion protein (PrP) abrogates the potential to rescue PrP-deficient mice from PrP-like protein/doppel-induced Neurodegeneration.

Atarashi R, Nishida N, Shigematsu K, Goto S, Kondo T, Sakaguchi S, Katamine S. Atarashi R, et al. Among authors: shigematsu k. J Biol Chem. 2003 Aug 1;278(31):28944-9. doi: 10.1074/jbc.M303655200. Epub 2003 May 19. J Biol Chem. 2003. PMID: 12759361 Free article.

2

Doppel-induced Purkinje cell death is stoichiometrically abrogated by prion protein.

Yamaguchi N, Sakaguchi S, Shigematsu K, Okimura N, Katamine S. Yamaguchi N, et al. Among authors: shigematsu k. Biochem Biophys Res Commun. 2004 Jul 9;319(4):1247-52. doi: 10.1016/j.bbrc.2004.05.115. Biochem Biophys Res Commun. 2004. PMID: 15194501

3

Dominant-negative effects of the N-terminal half of prion protein on neurotoxicity of prion protein-like protein/doppel in mice.

Yoshikawa D, Yamaguchi N, Ishibashi D, Yamanaka H, Okimura N, Yamaguchi Y, Mori T, Miyata H, Shigematsu K, Katamine S, Sakaguchi S. Yoshikawa D, et al. Among authors: shigematsu k. J Biol Chem. 2008 Aug 29;283(35):24202-11. doi: 10.1074/jbc.M804212200. Epub 2008 Jun 18. J Biol Chem. 2008. PMID: 18562311 Free PMC article.

4

A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination.

Nishida N, Tremblay P, Sugimoto T, Shigematsu K, Shirabe S, Petromilli C, Erpel SP, Nakaoke R, Atarashi R, Houtani T, Torchia M, Sakaguchi S, DeArmond SJ, Prusiner SB, Katamine S. Nishida N, et al. Among authors: shigematsu k. Lab Invest. 1999 Jun;79(6):689-97. Lab Invest. 1999. PMID: 10378511

5

Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to Purkinje cell degeneration.

Li A, Sakaguchi S, Shigematsu K, Atarashi R, Roy BC, Nakaoke R, Arima K, Okimura N, Kopacek J, Katamine S. Li A, et al. Among authors: shigematsu k. Am J Pathol. 2000 Nov;157(5):1447-52. doi: 10.1016/S0002-9440(10)64782-7. Am J Pathol. 2000. PMID: 11073804 Free PMC article.

6

Abnormal activation of glial cells in the brains of prion protein-deficient mice ectopically expressing prion protein-like protein, PrPLP/Dpl.

Atarashi R, Sakaguchi S, Shigematsu K, Arima K, Okimura N, Yamaguchi N, Li A, Kopacek J, Katamine S. Atarashi R, et al. Among authors: shigematsu k. Mol Med. 2001 Dec;7(12):803-9. Mol Med. 2001. PMID: 11844868 Free PMC article.

7

Biological and biochemical characteristics of prion strains conserved in persistently infected cell cultures.

Arima K, Nishida N, Sakaguchi S, Shigematsu K, Atarashi R, Yamaguchi N, Yoshikawa D, Yoon J, Watanabe K, Kobayashi N, Mouillet-Richard S, Lehmann S, Katamine S. Arima K, et al. Among authors: shigematsu k. J Virol. 2005 Jun;79(11):7104-12. doi: 10.1128/JVI.79.11.7104-7112.2005. J Virol. 2005. PMID: 15890950 Free PMC article.

8

Late-onset olfactory deficits and mitral cell loss in mice lacking prion protein with ectopic expression of Doppel.

Kim CK, Sakudo A, Taniuchi Y, Shigematsu K, Kang CB, Saeki K, Matsumoto Y, Sakaguchi S, Itohara S, Onodera T. Kim CK, et al. Among authors: shigematsu k. Int J Mol Med. 2007 Aug;20(2):169-76. Int J Mol Med. 2007. PMID: 17611634

9

FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice.

Nakagaki T, Satoh K, Ishibashi D, Fuse T, Sano K, Kamatari YO, Kuwata K, Shigematsu K, Iwamaru Y, Takenouchi T, Kitani H, Nishida N, Atarashi R. Nakagaki T, et al. Among authors: shigematsu k. Autophagy. 2013 Sep;9(9):1386-94. doi: 10.4161/auto.25381. Epub 2013 Jun 19. Autophagy. 2013. PMID: 23800841 Free article.

10

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene.

Sakaguchi S, Katamine S, Nishida N, Moriuchi R, Shigematsu K, Sugimoto T, Nakatani A, Kataoka Y, Houtani T, Shirabe S, Okada H, Hasegawa S, Miyamoto T, Noda T. Sakaguchi S, et al. Among authors: shigematsu k. Nature. 1996 Apr 11;380(6574):528-31. doi: 10.1038/380528a0. Nature. 1996. PMID: 8606772

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