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Page 1
Effective combination of ET-743 and doxorubicin in sarcoma: preclinical studies.
Meco D, Colombo T, Ubezio P, Zucchetti M, Zaffaroni M, Riccardi A, Faircloth G, Jose J, D'Incalci M, Riccardi R. Meco D, et al. Among authors: zaffaroni m. Cancer Chemother Pharmacol. 2003 Aug;52(2):131-8. doi: 10.1007/s00280-003-0636-6. Epub 2003 May 29. Cancer Chemother Pharmacol. 2003. PMID: 12783202
Fetal bovine serum, but not human serum, inhibits the in vitro cytotoxicity of ET-743 (Yondelis, trabectedin), an example of potential problems for extrapolation of active drug concentrations from in vitro studies.
Tognon G, Frapolli R, Zaffaroni M, Erba E, Zucchetti M, Faircloth GT, D'Incalci M. Tognon G, et al. Among authors: zaffaroni m. Cancer Chemother Pharmacol. 2004 Jan;53(1):89-90. doi: 10.1007/s00280-003-0704-y. Epub 2003 Oct 28. Cancer Chemother Pharmacol. 2004. PMID: 14586558 No abstract available.
Dietary agent indole-3-carbinol protects female rats against the hepatotoxicity of the antitumor drug ET-743 (trabectidin) without compromising efficacy in a rat mammary carcinoma.
Donald S, Verschoyle RD, Greaves P, Colombo T, Zucchetti M, Falcioni C, Zaffaroni M, D'Incalci M, Manson MM, Jimeno J, Steward WP, Gescher AJ. Donald S, et al. Among authors: zaffaroni m. Int J Cancer. 2004 Oct 10;111(6):961-7. doi: 10.1002/ijc.20356. Int J Cancer. 2004. PMID: 15300810
A novel taxane active against an orthotopically growing human glioma xenograft.
Laccabue D, Tortoreto M, Veneroni S, Perego P, Scanziani E, Zucchetti M, Zaffaroni M, D'Incalci M, Bombardelli E, Zunino F, Pratesi G. Laccabue D, et al. Among authors: zaffaroni m. Cancer. 2001 Dec 15;92(12):3085-92. doi: 10.1002/1097-0142(20011215)92:12<3085::aid-cncr10150>3.0.co;2-s. Cancer. 2001. PMID: 11753988
Pharmacokinetics and metabolism in mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a new oral c-seco-taxane derivative with antiangiogenic property effective on paclitaxel-resistant tumors.
Frapolli R, Marangon E, Zaffaroni M, Colombo T, Falcioni C, Bagnati R, Simone M, D'Incalci M, Manzotti C, Fontana G, Morazzoni P, Zucchetti M. Frapolli R, et al. Among authors: zaffaroni m. Drug Metab Dispos. 2006 Dec;34(12):2028-35. doi: 10.1124/dmd.106.012153. Epub 2006 Sep 8. Drug Metab Dispos. 2006. PMID: 16963486
349 results