Darwiche R - Search Results

1

Fas is detectable on beta cells in accelerated, but not spontaneous, diabetes in nonobese diabetic mice.

Darwiche R, Chong MM, Santamaria P, Thomas HE, Kay TW. Darwiche R, et al. J Immunol. 2003 Jun 15;170(12):6292-7. doi: 10.4049/jimmunol.170.12.6292. J Immunol. 2003. PMID: 12794162

2

Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production.

Thomas HE, Darwiche R, Corbett JA, Kay TW. Thomas HE, et al. Among authors: darwiche r. Diabetes. 2002 Feb;51(2):311-6. doi: 10.2337/diabetes.51.2.311. Diabetes. 2002. PMID: 11812737

3

IL-1 receptor deficiency slows progression to diabetes in the NOD mouse.

Thomas HE, Irawaty W, Darwiche R, Brodnicki TC, Santamaria P, Allison J, Kay TW. Thomas HE, et al. Among authors: darwiche r. Diabetes. 2004 Jan;53(1):113-21. doi: 10.2337/diabetes.53.1.113. Diabetes. 2004. PMID: 14693705

4

Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

Chong MM, Chen Y, Darwiche R, Dudek NL, Irawaty W, Santamaria P, Allison J, Kay TW, Thomas HE. Chong MM, et al. Among authors: darwiche r. J Immunol. 2004 May 1;172(9):5714-21. doi: 10.4049/jimmunol.172.9.5714. J Immunol. 2004. PMID: 15100317

5

Severe pancreatitis with exocrine destruction and increased islet neogenesis in mice with suppressor of cytokine signaling-1 deficiency.

Chen Y, Chong MM, Darwiche R, Thomas HE, Kay TW. Chen Y, et al. Among authors: darwiche r. Am J Pathol. 2004 Sep;165(3):913-21. doi: 10.1016/S0002-9440(10)63353-6. Am J Pathol. 2004. PMID: 15331415 Free PMC article.

6

In vivo effects of cytokines on pancreatic beta-cells in models of type I diabetes dependent on CD4(+) T lymphocytes.

Angstetra E, Graham KL, Emmett S, Dudek NL, Darwiche R, Ayala-Perez R, Allison J, Santamaria P, Kay TW, Thomas HE. Angstetra E, et al. Among authors: darwiche r. Immunol Cell Biol. 2009 Feb;87(2):178-85. doi: 10.1038/icb.2008.81. Epub 2008 Nov 18. Immunol Cell Biol. 2009. PMID: 19015667

7

Evidence that beta cell death in the nonobese diabetic mouse is Fas independent.

Thomas HE, Darwiche R, Corbett JA, Kay TW. Thomas HE, et al. Among authors: darwiche r. J Immunol. 1999 Aug 1;163(3):1562-9. J Immunol. 1999. PMID: 10415060

8

The role of cytokines as effectors of tissue destruction in autoimmunity.

Kay TW, Darwiche R, Irawaty W, Chong MM, Pennington HL, Thomas HE. Kay TW, et al. Among authors: darwiche r. Adv Exp Med Biol. 2003;520:73-86. doi: 10.1007/978-1-4615-0171-8_5. Adv Exp Med Biol. 2003. PMID: 12613573 No abstract available.

9

Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other gamma c-dependent cytokines in peripheral T cells.

Cornish AL, Chong MM, Davey GM, Darwiche R, Nicola NA, Hilton DJ, Kay TW, Starr R, Alexander WS. Cornish AL, et al. Among authors: darwiche r. J Biol Chem. 2003 Jun 20;278(25):22755-61. doi: 10.1074/jbc.M303021200. Epub 2003 Mar 28. J Biol Chem. 2003. PMID: 12665516 Free article.

10

Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation.

Chong MM, Cornish AL, Darwiche R, Stanley EG, Purton JF, Godfrey DI, Hilton DJ, Starr R, Alexander WS, Kay TW. Chong MM, et al. Among authors: darwiche r. Immunity. 2003 Apr;18(4):475-87. doi: 10.1016/s1074-7613(03)00078-5. Immunity. 2003. PMID: 12705851 Free article.

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