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Priming of naive CD8+ T cells in the presence of IL-12 selectively enhances the survival of CD8+CD62Lhi cells and results in superior anti-tumor activity in a tolerogenic murine model.
Díaz-Montero CM, El Naggar S, Al Khami A, El Naggar R, Montero AJ, Cole DJ, Salem ML. Díaz-Montero CM, et al. Among authors: montero aj. Cancer Immunol Immunother. 2008 Apr;57(4):563-72. doi: 10.1007/s00262-007-0394-0. Epub 2007 Aug 28. Cancer Immunol Immunother. 2008. PMID: 17726606 Free PMC article.
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy.
Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ, Montero AJ. Diaz-Montero CM, et al. Among authors: montero aj. Cancer Immunol Immunother. 2009 Jan;58(1):49-59. doi: 10.1007/s00262-008-0523-4. Epub 2008 Apr 30. Cancer Immunol Immunother. 2009. PMID: 18446337 Free PMC article.
Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C).
Salem ML, Díaz-Montero CM, Al-Khami AA, El-Naggar SA, Naga O, Montero AJ, Khafagy A, Cole DJ. Salem ML, et al. Among authors: montero aj. J Immunol. 2009 Feb 15;182(4):2030-40. doi: 10.4049/jimmunol.0801829. J Immunol. 2009. PMID: 19201856 Free PMC article.
A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.
Solito S, Falisi E, Diaz-Montero CM, Doni A, Pinton L, Rosato A, Francescato S, Basso G, Zanovello P, Onicescu G, Garrett-Mayer E, Montero AJ, Bronte V, Mandruzzato S. Solito S, et al. Among authors: montero aj. Blood. 2011 Aug 25;118(8):2254-65. doi: 10.1182/blood-2010-12-325753. Epub 2011 Jul 6. Blood. 2011. PMID: 21734236 Free PMC article.
173 results