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CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.
Tippin TK, Hamilton G, Moore L, Beaudet EJ, Jolley S, Brodie TA, Andrews RC, Becherer JD, McDougald DL, Gaul MD, Hoivik DJ, Mellon-Kusibab K, Lehmann J, Kliewer S, Novick S, Laethem R, Zhao Z, LeCluyse EL. Tippin TK, et al. Among authors: jolley s. Drug Metab Dispos. 2003 Jul;31(7):870-7. doi: 10.1124/dmd.31.7.870. Drug Metab Dispos. 2003. PMID: 12814963
CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.
Luo G, Cunningham M, Kim S, Burn T, Lin J, Sinz M, Hamilton G, Rizzo C, Jolley S, Gilbert D, Downey A, Mudra D, Graham R, Carroll K, Xie J, Madan A, Parkinson A, Christ D, Selling B, LeCluyse E, Gan LS. Luo G, et al. Among authors: jolley s. Drug Metab Dispos. 2002 Jul;30(7):795-804. doi: 10.1124/dmd.30.7.795. Drug Metab Dispos. 2002. PMID: 12065438
Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo.
Sahi J, Stern RH, Milad MA, Rose KA, Gibson G, Zheng X, Stilgenbauer L, Sadagopan N, Jolley S, Gilbert D, LeCluyse EL. Sahi J, et al. Among authors: jolley s. Drug Metab Dispos. 2004 Dec;32(12):1370-6. doi: 10.1124/dmd.104.000208. Epub 2004 Aug 27. Drug Metab Dispos. 2004. PMID: 15333513
Isolation and culture of primary human hepatocytes.
LeCluyse EL, Alexandre E, Hamilton GA, Viollon-Abadie C, Coon DJ, Jolley S, Richert L. LeCluyse EL, et al. Among authors: jolley s. Methods Mol Biol. 2005;290:207-29. doi: 10.1385/1-59259-838-2:207. Methods Mol Biol. 2005. PMID: 15361665
200 results