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Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice.
Keerthisingam CB, Jenkins RG, Harrison NK, Hernandez-Rodriguez NA, Booth H, Laurent GJ, Hart SL, Foster ML, McAnulty RJ. Keerthisingam CB, et al. Am J Pathol. 2001 Apr;158(4):1411-22. doi: 10.1016/s0002-9440(10)64092-8. Am J Pathol. 2001. PMID: 11290559 Free PMC article.