Schmitz JC - Search Results

1

Thymidylate synthase inhibitors as anticancer agents: from bench to bedside.

Chu E, Callender MA, Farrell MP, Schmitz JC. Chu E, et al. Among authors: schmitz jc. Cancer Chemother Pharmacol. 2003 Jul;52 Suppl 1:S80-9. doi: 10.1007/s00280-003-0625-9. Epub 2003 Jun 18. Cancer Chemother Pharmacol. 2003. PMID: 12819937 Review.

2

Repression of human thymidylate synthase mRNA translation by antisense 2'-O-methyl oligoribonucleotides.

Schmitz JC, Agrawal S, Chu E. Schmitz JC, et al. Antisense Nucleic Acid Drug Dev. 1998 Oct;8(5):371-8. doi: 10.1089/oli.1.1998.8.371. Antisense Nucleic Acid Drug Dev. 1998. PMID: 9826264

3

An immunoprecipitation-RNA:rPCR method for the in vivo isolation of ribonucleoprotein complexes.

Chu E, Schmitz JC, Ju J, Copur SM. Chu E, et al. Among authors: schmitz jc. Methods Mol Biol. 1999;118:265-74. doi: 10.1385/1-59259-676-2:265. Methods Mol Biol. 1999. PMID: 10549529 No abstract available.

4

Effect of 2'-O-methyl antisense ORNs on expression of thymidylate synthase in human colon cancer RKO cells.

Schmitz JC, Yu D, Agrawal S, Chu E. Schmitz JC, et al. Nucleic Acids Res. 2001 Jan 15;29(2):415-22. doi: 10.1093/nar/29.2.415. Nucleic Acids Res. 2001. PMID: 11139611 Free PMC article.

5

Translational regulation as a novel mechanism for the development of cellular drug resistance.

Schmitz JC, Liu J, Lin X, Chen TM, Yan W, Tai N, Gollerkeri A, Chu E. Schmitz JC, et al. Cancer Metastasis Rev. 2001;20(1-2):33-41. doi: 10.1023/a:1013100306315. Cancer Metastasis Rev. 2001. PMID: 11831645 Review.

6

Thymidylate synthase as a translational regulator of cellular gene expression.

Liu J, Schmitz JC, Lin X, Tai N, Yan W, Farrell M, Bailly M, Chen Tm, Chu E. Liu J, et al. Among authors: schmitz jc. Biochim Biophys Acta. 2002 Jul 18;1587(2-3):174-82. doi: 10.1016/s0925-4439(02)00080-7. Biochim Biophys Acta. 2002. PMID: 12084459 Free article. Review.

7

Identification of critical amino acid residues on human dihydrofolate reductase protein that mediate RNA recognition.

Tai N, Ding Y, Schmitz JC, Chu E. Tai N, et al. Among authors: schmitz jc. Nucleic Acids Res. 2002 Oct 15;30(20):4481-8. doi: 10.1093/nar/gkf562. Nucleic Acids Res. 2002. PMID: 12384595 Free PMC article.

8

Thymidylate synthase: a critical target for cancer chemotherapy.

Rose MG, Farrell MP, Schmitz JC. Rose MG, et al. Among authors: schmitz jc. Clin Colorectal Cancer. 2002 Feb;1(4):220-9. doi: 10.3816/CCC.2002.n.003. Clin Colorectal Cancer. 2002. PMID: 12450420 Review.

9

Characterization of a cis-acting regulatory element in the protein-coding region of human dihydrofolate reductase mRNA.

Tai N, Schmitz JC, Chen TM, Chu E. Tai N, et al. Among authors: schmitz jc. Biochem J. 2004 Mar 15;378(Pt 3):999-1006. doi: 10.1042/BJ20031396. Biochem J. 2004. PMID: 14664697 Free PMC article.

10

Small interfering double-stranded RNAs as therapeutic molecules to restore chemosensitivity to thymidylate synthase inhibitor compounds.

Schmitz JC, Chen TM, Chu E. Schmitz JC, et al. Cancer Res. 2004 Feb 15;64(4):1431-5. doi: 10.1158/0008-5472.can-03-1203. Cancer Res. 2004. PMID: 14973067

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