Peiper SC - Search Results

1

Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2.

Alvarez Arias D, Navenot JM, Zhang WB, Broach J, Peiper SC. Alvarez Arias D, et al. Among authors: peiper sc. J Biol Chem. 2003 Sep 19;278(38):36513-21. doi: 10.1074/jbc.M303739200. Epub 2003 Jul 1. J Biol Chem. 2003. PMID: 12837756 Free article.

2

A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists.

Zhang WB, Navenot JM, Haribabu B, Tamamura H, Hiramatu K, Omagari A, Pei G, Manfredi JP, Fujii N, Broach JR, Peiper SC. Zhang WB, et al. Among authors: peiper sc. J Biol Chem. 2002 Jul 5;277(27):24515-21. doi: 10.1074/jbc.M200889200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923301 Free article.

3

Characterization of constitutively active mutants of G protein-coupled receptors.

Navenot JM, Wang ZX, Peiper SC. Navenot JM, et al. Among authors: peiper sc. Methods Mol Biol. 2006;332:129-39. doi: 10.1385/1-59745-048-0:129. Methods Mol Biol. 2006. PMID: 16878689

4

Association of nucleophosmin negatively regulates CXCR4-mediated G protein activation and chemotaxis.

Zhang W, Navenot JM, Frilot NM, Fujii N, Peiper SC. Zhang W, et al. Among authors: peiper sc. Mol Pharmacol. 2007 Nov;72(5):1310-21. doi: 10.1124/mol.107.037119. Epub 2007 Aug 22. Mol Pharmacol. 2007. PMID: 17715399

5

Kisspeptin-10-induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: a potential mechanism for the metastasis suppressor activity of kisspeptins.

Navenot JM, Wang Z, Chopin M, Fujii N, Peiper SC. Navenot JM, et al. Among authors: peiper sc. Cancer Res. 2005 Nov 15;65(22):10450-6. doi: 10.1158/0008-5472.CAN-05-1757. Cancer Res. 2005. PMID: 16288036

6

Functional expression of CXCR4 in Saccharomyces cerevisiae in the development of powerful tools for the pharmacological characterization of CXCR4.

Wang ZX, Broach JR, Peiper SC. Wang ZX, et al. Among authors: peiper sc. Methods Mol Biol. 2006;332:115-27. doi: 10.1385/1-59745-048-0:115. Methods Mol Biol. 2006. PMID: 16878688

7

KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis.

Navenot JM, Fujii N, Peiper SC. Navenot JM, et al. Among authors: peiper sc. Mol Pharmacol. 2009 May;75(5):1074-83. doi: 10.1124/mol.108.054270. Epub 2009 Feb 6. Mol Pharmacol. 2009. PMID: 19201817

8

Activation of Rho and Rho-associated kinase by GPR54 and KiSS1 metastasis suppressor gene product induces changes of cell morphology and contributes to apoptosis.

Navenot JM, Fujii N, Peiper SC. Navenot JM, et al. Among authors: peiper sc. Mol Pharmacol. 2009 Jun;75(6):1300-6. doi: 10.1124/mol.109.055095. Epub 2009 Mar 13. Mol Pharmacol. 2009. PMID: 19286835

9

Functional expression of CXCR4 in S. cerevisiae: development of tools for mechanistic and pharmacologic studies.

Zhang WB, Wang ZX, Murray JL, Fujii N, Broach J, Peiper SC. Zhang WB, et al. Among authors: peiper sc. Ernst Schering Res Found Workshop. 2004;(45):125-52. doi: 10.1007/978-3-662-05403-1_9. Ernst Schering Res Found Workshop. 2004. PMID: 14699798 No abstract available.

10

Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity.

Niida A, Wang Z, Tomita K, Oishi S, Tamamura H, Otaka A, Navenot JM, Broach JR, Peiper SC, Fujii N. Niida A, et al. Among authors: peiper sc. Bioorg Med Chem Lett. 2006 Jan 1;16(1):134-7. doi: 10.1016/j.bmcl.2005.09.054. Epub 2005 Oct 18. Bioorg Med Chem Lett. 2006. PMID: 16242330

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