Li R - Search Results

1

Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline.

Stapon A, Li R, Townsend CA. Stapon A, et al. Among authors: li r. J Am Chem Soc. 2003 Jul 16;125(28):8486-93. doi: 10.1021/ja034248a. J Am Chem Soc. 2003. PMID: 12848554

2

beta-Lactam synthetase: a new biosynthetic enzyme.

Bachmann BO, Li R, Townsend CA. Bachmann BO, et al. Among authors: li r. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9082-6. doi: 10.1073/pnas.95.16.9082. Proc Natl Acad Sci U S A. 1998. PMID: 9689037 Free PMC article.

3

Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus.

Li R, Khaleeli N, Townsend CA. Li R, et al. J Bacteriol. 2000 Jul;182(14):4087-95. doi: 10.1128/JB.182.14.4087-4095.2000. J Bacteriol. 2000. PMID: 10869089 Free PMC article.

4

Synthesis of (3S,5R)-carbapenam-3-carboxylic acid and its role in carbapenem biosynthesis and the stereoinversion problem.

Stapon A, Li R, Townsend CA. Stapon A, et al. Among authors: li r. J Am Chem Soc. 2003 Dec 24;125(51):15746-7. doi: 10.1021/ja037665w. J Am Chem Soc. 2003. PMID: 14677956

5

Rational strain improvement for enhanced clavulanic acid production by genetic engineering of the glycolytic pathway in Streptomyces clavuligerus.

Li R, Townsend CA. Li R, et al. Metab Eng. 2006 May;8(3):240-52. doi: 10.1016/j.ymben.2006.01.003. Epub 2006 Mar 10. Metab Eng. 2006. PMID: 16530442

6

Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis.

Freeman MF, Moshos KA, Bodner MJ, Li R, Townsend CA. Freeman MF, et al. Among authors: li r. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11128-33. doi: 10.1073/pnas.0804500105. Epub 2008 Aug 4. Proc Natl Acad Sci U S A. 2008. PMID: 18678912 Free PMC article.

7

Non-heme iron oxygenases generate natural structural diversity in carbapenem antibiotics.

Bodner MJ, Phelan RM, Freeman MF, Li R, Townsend CA. Bodner MJ, et al. Among authors: li r. J Am Chem Soc. 2010 Jan 13;132(1):12-3. doi: 10.1021/ja907320n. J Am Chem Soc. 2010. PMID: 20017478 Free PMC article.

8

Definition of the common and divergent steps in carbapenem β-lactam antibiotic biosynthesis.

Bodner MJ, Li R, Phelan RM, Freeman MF, Moshos KA, Lloyd EP, Townsend CA. Bodner MJ, et al. Among authors: li r. Chembiochem. 2011 Sep 19;12(14):2159-65. doi: 10.1002/cbic.201100366. Epub 2011 Aug 24. Chembiochem. 2011. PMID: 21913298 Free PMC article.

9

Identification and characterization of the carbapenem MM 4550 and its gene cluster in Streptomyces argenteolus ATCC 11009.

Li R, Lloyd EP, Moshos KA, Townsend CA. Li R, et al. Chembiochem. 2014 Jan 24;15(2):320-31. doi: 10.1002/cbic.201300319. Epub 2014 Jan 13. Chembiochem. 2014. PMID: 24420617 Free PMC article.

10

Identification and Characterization of the Sulfazecin Monobactam Biosynthetic Gene Cluster.

Li R, Oliver RA, Townsend CA. Li R, et al. Cell Chem Biol. 2017 Jan 19;24(1):24-34. doi: 10.1016/j.chembiol.2016.11.010. Epub 2016 Dec 22. Cell Chem Biol. 2017. PMID: 28017601 Free PMC article.

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