Johnson JL - Search Results

1

Inhibitors tethered near the acetylcholinesterase active site serve as molecular rulers of the peripheral and acylation sites.

Johnson JL, Cusack B, Hughes TF, McCullough EH, Fauq A, Romanovskis P, Spatola AF, Rosenberry TL. Johnson JL, et al. J Biol Chem. 2003 Oct 3;278(40):38948-55. doi: 10.1074/jbc.M304797200. Epub 2003 Jul 8. J Biol Chem. 2003. PMID: 12851386 Free article.

2

Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate.

Johnson JL, Cusack B, Davies MP, Fauq A, Rosenberry TL. Johnson JL, et al. Biochemistry. 2003 May 13;42(18):5438-52. doi: 10.1021/bi027065u. Biochemistry. 2003. PMID: 12731886

3

Interactions between the peripheral site and the acylation site in acetylcholinesterase.

Rosenberry TL, Johnson JL, Cusack B, Thomas JL, Emani S, Venkatasubban KS. Rosenberry TL, et al. Among authors: johnson jl. Chem Biol Interact. 2005 Dec 15;157-158:181-9. doi: 10.1016/j.cbi.2005.10.027. Epub 2005 Oct 27. Chem Biol Interact. 2005. PMID: 16256966

4

A novel strategy for protection against organophosphate toxicity: Evolution of cyclic inhibitors with high affinity for the acetylcholinesterase peripheral site.

Cusack B, Romanovskis P, Johnson JL, Etienne G, Rosenberry TL. Cusack B, et al. Among authors: johnson jl. Chem Biol Interact. 2005 Dec 15;157-158:370. doi: 10.1016/j.cbi.2005.10.056. Chem Biol Interact. 2005. PMID: 16429491 No abstract available.

5

Monitoring the reaction of carbachol with acetylcholinesterase by thioflavin T fluorescence and acetylthiocholine hydrolysis.

Rosenberry TL, Sonoda LK, Dekat SE, Cusack B, Johnson JL. Rosenberry TL, et al. Among authors: johnson jl. Chem Biol Interact. 2008 Sep 25;175(1-3):235-41. doi: 10.1016/j.cbi.2008.06.002. Epub 2008 Jun 17. Chem Biol Interact. 2008. PMID: 18602908 Free PMC article.

6

Molecular basis of inhibition of substrate hydrolysis by a ligand bound to the peripheral site of acetylcholinesterase.

Auletta JT, Johnson JL, Rosenberry TL. Auletta JT, et al. Among authors: johnson jl. Chem Biol Interact. 2010 Sep 6;187(1-3):135-41. doi: 10.1016/j.cbi.2010.05.009. Epub 2010 May 21. Chem Biol Interact. 2010. PMID: 20493829 Free PMC article.

7

Measuring carbamoylation and decarbamoylation rate constants by continuous assay of AChE.

Johnson JL, Thomas JL, Emani S, Cusack B, Rosenberry TL. Johnson JL, et al. Chem Biol Interact. 2005 Dec 15;157-158:384-5. doi: 10.1016/j.cbi.2005.10.066. Chem Biol Interact. 2005. PMID: 16429515 No abstract available.

8

Steric effects in the decarbamoylation of carbamoylated acetylcholinesterases.

Venkatasubban KS, Johnson JL, Thomas JL, Fauq A, Cusack B, Rosenberry TL. Venkatasubban KS, et al. Among authors: johnson jl. Chem Biol Interact. 2005 Dec 15;157-158:433-4. doi: 10.1016/j.cbi.2005.10.094. Chem Biol Interact. 2005. PMID: 16429582 No abstract available.

9

Analysis of the reaction of carbachol with acetylcholinesterase using thioflavin T as a coupled fluorescence reporter.

Rosenberry TL, Sonoda LK, Dekat SE, Cusack B, Johnson JL. Rosenberry TL, et al. Among authors: johnson jl. Biochemistry. 2008 Dec 9;47(49):13056-63. doi: 10.1021/bi8015197. Biochemistry. 2008. PMID: 19006330 Free PMC article.

10

Decarbamoylation of acetylcholinesterases is markedly slowed as carbamoyl groups increase in size.

Venkatasubban KS, Johnson JL, Thomas JL, Fauq A, Cusack B, Rosenberry TL. Venkatasubban KS, et al. Among authors: johnson jl. Arch Biochem Biophys. 2018 Oct 1;655:67-74. doi: 10.1016/j.abb.2018.08.006. Epub 2018 Aug 9. Arch Biochem Biophys. 2018. PMID: 30098983 Free PMC article.

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