Yan C - Search Results

1

WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility.

Yan C, Martinez-Quiles N, Eden S, Shibata T, Takeshima F, Shinkura R, Fujiwara Y, Bronson R, Snapper SB, Kirschner MW, Geha R, Rosen FS, Alt FW. Yan C, et al. EMBO J. 2003 Jul 15;22(14):3602-12. doi: 10.1093/emboj/cdg350. EMBO J. 2003. PMID: 12853475 Free PMC article.

2

Mismatch repair proteins MSH2, MLH1, and EXO1 are important for class-switch recombination events occurring in B cells that lack nonhomologous end joining.

Eccleston J, Yan C, Yuan K, Alt FW, Selsing E. Eccleston J, et al. Among authors: yan c. J Immunol. 2011 Feb 15;186(4):2336-43. doi: 10.4049/jimmunol.1003104. Epub 2011 Jan 17. J Immunol. 2011. PMID: 21242524 Free PMC article.

3

XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice.

Yan CT, Kaushal D, Murphy M, Zhang Y, Datta A, Chen C, Monroe B, Mostoslavsky G, Coakley K, Gao Y, Mills KD, Fazeli AP, Tepsuporn S, Hall G, Mulligan R, Fox E, Bronson R, De Girolami U, Lee C, Alt FW. Yan CT, et al. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7378-83. doi: 10.1073/pnas.0601938103. Epub 2006 May 2. Proc Natl Acad Sci U S A. 2006. PMID: 16670198 Free PMC article.

4

Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair.

Xie A, Hartlerode A, Stucki M, Odate S, Puget N, Kwok A, Nagaraju G, Yan C, Alt FW, Chen J, Jackson SP, Scully R. Xie A, et al. Among authors: yan c. Mol Cell. 2007 Dec 28;28(6):1045-57. doi: 10.1016/j.molcel.2007.12.005. Mol Cell. 2007. PMID: 18158901 Free PMC article.

5

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX.

Bassing CH, Chua KF, Sekiguchi J, Suh H, Whitlow SR, Fleming JC, Monroe BC, Ciccone DN, Yan C, Vlasakova K, Livingston DM, Ferguson DO, Scully R, Alt FW. Bassing CH, et al. Among authors: yan c. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8173-8. doi: 10.1073/pnas.122228699. Epub 2002 May 28. Proc Natl Acad Sci U S A. 2002. PMID: 12034884 Free PMC article.

6

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.

Boboila C, Yan C, Wesemann DR, Jankovic M, Wang JH, Manis J, Nussenzweig A, Nussenzweig M, Alt FW. Boboila C, et al. Among authors: yan c. J Exp Med. 2010 Feb 15;207(2):417-27. doi: 10.1084/jem.20092449. Epub 2010 Feb 8. J Exp Med. 2010. PMID: 20142431 Free PMC article.

7

Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.

Boboila C, Jankovic M, Yan CT, Wang JH, Wesemann DR, Zhang T, Fazeli A, Feldman L, Nussenzweig A, Nussenzweig M, Alt FW. Boboila C, et al. Among authors: yan ct. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3034-9. doi: 10.1073/pnas.0915067107. Epub 2010 Jan 25. Proc Natl Acad Sci U S A. 2010. PMID: 20133803 Free PMC article.

8

Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching.

Wang JH, Alt FW, Gostissa M, Datta A, Murphy M, Alimzhanov MB, Coakley KM, Rajewsky K, Manis JP, Yan CT. Wang JH, et al. J Exp Med. 2008 Dec 22;205(13):3079-90. doi: 10.1084/jem.20082271. Epub 2008 Dec 8. J Exp Med. 2008. PMID: 19064702 Free PMC article.

9

Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.

Gostissa M, Yan CT, Bianco JM, Cogné M, Pinaud E, Alt FW. Gostissa M, et al. Nature. 2009 Dec 10;462(7274):803-7. doi: 10.1038/nature08633. Nature. 2009. PMID: 20010689 Free PMC article.

10

Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome.

Rucci F, Notarangelo LD, Fazeli A, Patrizi L, Hickernell T, Paganini T, Coakley KM, Detre C, Keszei M, Walter JE, Feldman L, Cheng HL, Poliani PL, Wang JH, Balter BB, Recher M, Andersson EM, Zha S, Giliani S, Terhorst C, Alt FW, Yan CT. Rucci F, et al. Among authors: yan ct. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3024-9. doi: 10.1073/pnas.0914865107. Epub 2010 Feb 1. Proc Natl Acad Sci U S A. 2010. PMID: 20133615 Free PMC article.

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