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Gastrointestinal Device-Mediated Delivery of mRNA-Lipid Nanoparticles Achieves Distinct Expression and Biodistribution in Mice and Pigs.
Schultz D, Kempen PJ, Primdahl S, Pereverzina M, Uhrenfeldt AH, Alba EMD, Andreasen J, Pedersen HD, Cleveland C, Duncombe T, Ahnfelt-Ro Nne J, Kirk RK, Pfander IB, Sticker D, Water JJ, Buckley ST, Andresen TL, Urquhart AJ. Schultz D, et al. Among authors: andresen tl. ACS Appl Mater Interfaces. 2024 Dec 11;16(49):67192-67202. doi: 10.1021/acsami.4c11819. Epub 2024 Dec 2. ACS Appl Mater Interfaces. 2024. PMID: 39621822
Gentamicin and clindamycin antibiotic-eluting depot technology eradicates S. aureus in an implant-associated osteomyelitis pig model without systemic antibiotics.
Henriksen NL, Serrano-Chávez E, Fuglsang-Madsen A, Jensen LK, Gottlieb H, Bue M, Andresen TL, Henriksen JR, Hansen AE. Henriksen NL, et al. Among authors: andresen tl. Antimicrob Agents Chemother. 2024 Oct 8;68(10):e0069124. doi: 10.1128/aac.00691-24. Epub 2024 Sep 17. Antimicrob Agents Chemother. 2024. PMID: 39287404 Free PMC article.
An in situ depot for the sustained release of a TLR7/8 agonist in combination with a TGFβ inhibitor promotes anti-tumor immune responses.
Jensen SB, Jæhger DE, Serrano-Chávez E, Halldórsdóttir HR, Engel TB, Jørgensen JS, Björgvinsdóttir UJ, Kostrikov S, Scheeper MJ, Ringgaard L, Bruun LM, Stavnsbjerg C, Christensen E, Bak M, Thuroczy J, Balogh L, Jensen ATI, Melander F, Kjaer A, Henriksen JR, Hansen AE, Andresen TL. Jensen SB, et al. Among authors: andresen tl. Nat Commun. 2024 Sep 3;15(1):7687. doi: 10.1038/s41467-024-50967-w. Nat Commun. 2024. PMID: 39227589 Free PMC article.
275 results