Liu Y - Search Results

1

Investigating the origin of the slow-binding inhibition of HCV NS3 serine protease by a novel substrate based inhibitor.

Liu Y, Saldivar A, Bess J, Solomon L, Chen CM, Tripathi R, Barrett L, Richardson PL, Molla A, Kohlbrenner W, Kati W. Liu Y, et al. Biochemistry. 2003 Jul 29;42(29):8862-9. doi: 10.1021/bi034661v. Biochemistry. 2003. PMID: 12873147

2

Hepatitis C NS3 protease inhibition by peptidyl-alpha-ketoamide inhibitors: kinetic mechanism and structure.

Liu Y, Stoll VS, Richardson PL, Saldivar A, Klaus JL, Molla A, Kohlbrenner W, Kati WM. Liu Y, et al. Arch Biochem Biophys. 2004 Jan 15;421(2):207-16. doi: 10.1016/j.abb.2003.11.013. Arch Biochem Biophys. 2004. PMID: 14984200

3

A fluorescence polarization-based assay for peptidyl prolyl cis/trans isomerase cyclophilin A.

Liu Y, Jiang J, Richardson PL, Reddy RD, Johnson DD, Kati WM. Liu Y, et al. Anal Biochem. 2006 Sep 1;356(1):100-7. doi: 10.1016/j.ab.2006.04.040. Epub 2006 May 12. Anal Biochem. 2006. PMID: 16737676

4

Mechanistic study of HCV polymerase inhibitors at individual steps of the polymerization reaction.

Liu Y, Jiang WW, Pratt J, Rockway T, Harris K, Vasavanonda S, Tripathi R, Pithawalla R, Kati WM. Liu Y, et al. Biochemistry. 2006 Sep 26;45(38):11312-23. doi: 10.1021/bi060511j. Biochemistry. 2006. PMID: 16981691

5

Methods to measure the intracellular concentration of unlabeled compounds within cultured cells using liquid chromatography/tandem mass spectrometry.

Colletti LM, Liu Y, Koev G, Richardson PL, Chen CM, Kati W. Colletti LM, et al. Among authors: liu y. Anal Biochem. 2008 Dec 15;383(2):186-93. doi: 10.1016/j.ab.2008.08.012. Epub 2008 Aug 22. Anal Biochem. 2008. PMID: 18790690

6

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines.

Pratt JK, Donner P, McDaniel KF, Maring CJ, Kati WM, Mo H, Middleton T, Liu Y, Ng T, Xie Q, Zhang R, Montgomery D, Molla A, Kempf DJ, Kohlbrenner W. Pratt JK, et al. Among authors: liu y. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1577-82. doi: 10.1016/j.bmcl.2005.01.071. Bioorg Med Chem Lett. 2005. PMID: 15745800

7

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides.

Krueger AC, Madigan DL, Jiang WW, Kati WM, Liu D, Liu Y, Maring CJ, Masse S, McDaniel KF, Middleton T, Mo H, Molla A, Montgomery D, Pratt JK, Rockway TW, Zhang R, Kempf DJ. Krueger AC, et al. Among authors: liu y, liu d. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3367-70. doi: 10.1016/j.bmcl.2006.04.015. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16650764

8

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of unsymmetrical 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives.

Krueger AC, Madigan DL, Green BE, Hutchinson DK, Jiang WW, Kati WM, Liu Y, Maring CJ, Masse SV, McDaniel KF, Middleton TR, Mo H, Molla A, Montgomery DA, Ng TI, Kempf DJ. Krueger AC, et al. Among authors: liu y. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2289-92. doi: 10.1016/j.bmcl.2007.01.072. Epub 2007 Jan 27. Bioorg Med Chem Lett. 2007. PMID: 17300933

9

Identification of halosalicylamide derivatives as a novel class of allosteric inhibitors of HCV NS5B polymerase.

Liu Y, Donner PL, Pratt JK, Jiang WW, Ng T, Gracias V, Baumeister S, Wiedeman PE, Traphagen L, Warrior U, Maring C, Kati WM, Djuric SW, Molla A. Liu Y, et al. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3173-7. doi: 10.1016/j.bmcl.2008.04.068. Epub 2008 May 1. Bioorg Med Chem Lett. 2008. PMID: 18479921

10

Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives.

Hutchinson DK, Rosenberg T, Klein LL, Bosse TD, Larson DP, He W, Jiang WW, Kati WM, Kohlbrenner WE, Liu Y, Masse SV, Middleton T, Molla A, Montgomery DA, Beno DW, Stewart KD, Stoll VS, Kempf DJ. Hutchinson DK, et al. Among authors: liu y. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3887-90. doi: 10.1016/j.bmcl.2008.06.043. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18599294

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