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Page 1
Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems.
Salonen JS, Nyman L, Boobis AR, Edwards RJ, Watts P, Lake BG, Price RJ, Renwick AB, Gómez-Lechón MJ, Castell JV, Ingelman-Sundberg M, Hidestrand M, Guillouzo A, Corcos L, Goldfarb PS, Lewis DF, Taavitsainen P, Pelkonen O. Salonen JS, et al. Among authors: taavitsainen p. Drug Metab Dispos. 2003 Sep;31(9):1093-102. doi: 10.1124/dmd.31.9.1093. Drug Metab Dispos. 2003. PMID: 12920164
An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant.
Andersson TB, Sjöberg H, Hoffmann KJ, Boobis AR, Watts P, Edwards RJ, Lake BG, Price RJ, Renwick AB, Gómez-Lechón MJ, Castell JV, Ingelman-Sundberg M, Hidestrand M, Goldfarb PS, Lewis DF, Corcos L, Guillouzo A, Taavitsainen P, Pelkonen O. Andersson TB, et al. Among authors: taavitsainen p. Drug Metab Dispos. 2001 May;29(5):712-20. Drug Metab Dispos. 2001. PMID: 11302938
Carbamazepine: a 'blind' assessment of CVP-associated metabolism and interactions in human liver-derived in vitro systems.
Pelkonen O, Myllynen P, Taavitsainen P, Boobis AR, Watts P, Lake BG, Price RJ, Renwick AB, Gómez-Lechón MJ, Castell JV, Ingelman-Sundberg M, Hidestrand M, Guillouzo A, Corcos L, Goldfarb PS, Lewis DF. Pelkonen O, et al. Among authors: taavitsainen p. Xenobiotica. 2001 Jun;31(6):321-43. doi: 10.1080/00498250110055479. Xenobiotica. 2001. PMID: 11513246
CYP2D6 polymorphism is not crucial for the disposition of selegiline.
Scheinin H, Anttila M, Dahl ML, Karnani H, Nyman L, Taavitsainen P, Pelkonen O, Bertilsson L. Scheinin H, et al. Among authors: taavitsainen p. Clin Pharmacol Ther. 1998 Oct;64(4):402-11. doi: 10.1016/S0009-9236(98)90071-6. Clin Pharmacol Ther. 1998. PMID: 9797797 Clinical Trial.
Inhibition and induction of human cytochrome P450 (CYP) enzymes.
Pelkonen O, Mäenpää J, Taavitsainen P, Rautio A, Raunio H. Pelkonen O, et al. Among authors: taavitsainen p. Xenobiotica. 1998 Dec;28(12):1203-53. doi: 10.1080/004982598238886. Xenobiotica. 1998. PMID: 9890159 Review. No abstract available.
25 results