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Src homology 2-domain containing leukocyte-specific phosphoprotein of 76 kDa is mandatory for TCR-mediated inside-out signaling, but dispensable for CXCR4-mediated LFA-1 activation, adhesion, and migration of T cells.
Horn J, Wang X, Reichardt P, Stradal TE, Warnecke N, Simeoni L, Gunzer M, Yablonski D, Schraven B, Kliche S. Horn J, et al. Among authors: schraven b. J Immunol. 2009 Nov 1;183(9):5756-67. doi: 10.4049/jimmunol.0900649. Epub 2009 Oct 7. J Immunol. 2009. PMID: 19812192
Sos1 regulates sustained TCR-mediated Erk activation.
Poltorak M, Meinert I, Stone JC, Schraven B, Simeoni L. Poltorak M, et al. Among authors: schraven b. Eur J Immunol. 2014 May;44(5):1535-40. doi: 10.1002/eji.201344046. Epub 2014 Feb 20. Eur J Immunol. 2014. PMID: 24497027 Free article. Clinical Trial.
SIT and TRIM determine T cell fate in the thymus.
Koelsch U, Schraven B, Simeoni L. Koelsch U, et al. Among authors: schraven b. J Immunol. 2008 Nov 1;181(9):5930-9. doi: 10.4049/jimmunol.181.9.5930. J Immunol. 2008. PMID: 18941181
217 results