Houghton JA - Search Results

1

Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.

Tillman DM, Izeradjene K, Szucs KS, Douglas L, Houghton JA. Tillman DM, et al. Among authors: houghton ja. Cancer Res. 2003 Aug 15;63(16):5118-25. Cancer Res. 2003. PMID: 12941843

2

Modulation of the Fas signaling pathway by IFN-gamma in therapy of colon cancer: phase I trial and correlative studies of IFN-gamma, 5-fluorouracil, and leucovorin.

Schwartzberg LS, Petak I, Stewart C, Turner PK, Ashley J, Tillman DM, Douglas L, Tan M, Billups C, Mihalik R, Weir A, Tauer K, Shope S, Houghton JA. Schwartzberg LS, et al. Among authors: houghton ja. Clin Cancer Res. 2002 Aug;8(8):2488-98. Clin Cancer Res. 2002. PMID: 12171874 Clinical Trial.

3

Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin.

Geller J, Petak I, Szucs KS, Nagy K, Tillman DM, Houghton JA. Geller J, et al. Among authors: houghton ja. Clin Cancer Res. 2003 Dec 15;9(17):6504-15. Clin Cancer Res. 2003. PMID: 14695155

4

Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells.

Izeradjene K, Douglas L, Delaney A, Houghton JA. Izeradjene K, et al. Among authors: houghton ja. Clin Cancer Res. 2004 Oct 1;10(19):6650-60. doi: 10.1158/1078-0432.CCR-04-0576. Clin Cancer Res. 2004. PMID: 15475455

5

Casein kinase I attenuates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by regulating the recruitment of fas-associated death domain and procaspase-8 to the death-inducing signaling complex.

Izeradjene K, Douglas L, Delaney AB, Houghton JA. Izeradjene K, et al. Among authors: houghton ja. Cancer Res. 2004 Nov 1;64(21):8036-44. doi: 10.1158/0008-5472.CAN-04-0762. Cancer Res. 2004. PMID: 15520213

6

Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines.

Izeradjene K, Douglas L, Delaney A, Houghton JA. Izeradjene K, et al. Among authors: houghton ja. Oncogene. 2005 Mar 17;24(12):2050-8. doi: 10.1038/sj.onc.1208397. Oncogene. 2005. PMID: 15688023

7

Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.

Izeradjene K, Douglas L, Tillman DM, Delaney AB, Houghton JA. Izeradjene K, et al. Among authors: houghton ja. Cancer Res. 2005 Aug 15;65(16):7436-45. doi: 10.1158/0008-5472.CAN-04-2628. Cancer Res. 2005. PMID: 16103097

8

Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels.

Nawrocki ST, Carew JS, Douglas L, Cleveland JL, Humphreys R, Houghton JA. Nawrocki ST, et al. Among authors: houghton ja. Cancer Res. 2007 Jul 15;67(14):6987-94. doi: 10.1158/0008-5472.CAN-07-0812. Cancer Res. 2007. PMID: 17638911

9

Thymineless death in colon carcinoma cells is mediated via fas signaling.

Houghton JA, Harwood FG, Tillman DM. Houghton JA, et al. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8144-9. doi: 10.1073/pnas.94.15.8144. Proc Natl Acad Sci U S A. 1997. PMID: 9223329 Free PMC article.

10

Selective sensitization to DNA-damaging agents in a human rhabdomyosarcoma cell line with inducible wild-type p53 overexpression.

Gibson AA, Harwood FG, Tillman DM, Houghton JA. Gibson AA, et al. Among authors: houghton ja. Clin Cancer Res. 1998 Jan;4(1):145-52. Clin Cancer Res. 1998. PMID: 9516963

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