Mayo KH - Search Results

1

Design of a partial peptide mimetic of anginex with antiangiogenic and anticancer activity.

Mayo KH, Dings RP, Flader C, Nesmelova I, Hargittai B, van der Schaft DW, van Eijk LI, Walek D, Haseman J, Hoye TR, Griffioen AW. Mayo KH, et al. J Biol Chem. 2003 Nov 14;278(46):45746-52. doi: 10.1074/jbc.M308608200. Epub 2003 Aug 28. J Biol Chem. 2003. PMID: 12947097 Free article.

2

Discovery and development of anti-angiogenic peptides: A structural link.

Dings RP, Nesmelova I, Griffioen AW, Mayo KH. Dings RP, et al. Among authors: mayo kh. Angiogenesis. 2003;6(2):83-91. doi: 10.1023/B:AGEN.0000011730.94233.06. Angiogenesis. 2003. PMID: 14739615 Review.

3

Platelet factor 4 and interleukin-8 CXC chemokine heterodimer formation modulates function at the quaternary structural level.

Nesmelova IV, Sham Y, Dudek AZ, van Eijk LI, Wu G, Slungaard A, Mortari F, Griffioen AW, Mayo KH. Nesmelova IV, et al. Among authors: mayo kh. J Biol Chem. 2005 Feb 11;280(6):4948-58. doi: 10.1074/jbc.M405364200. Epub 2004 Nov 5. J Biol Chem. 2005. PMID: 15531763 Free article.

4

Anginex synergizes with radiation therapy to inhibit tumor growth by radiosensitizing endothelial cells.

Dings RP, Williams BW, Song CW, Griffioen AW, Mayo KH, Griffin RJ. Dings RP, et al. Among authors: mayo kh. Int J Cancer. 2005 Jun 10;115(2):312-9. doi: 10.1002/ijc.20850. Int J Cancer. 2005. PMID: 15688384

5

Design of nonpeptidic topomimetics of antiangiogenic proteins with antitumor activities.

Dings RP, Chen X, Hellebrekers DM, van Eijk LI, Zhang Y, Hoye TR, Griffioen AW, Mayo KH. Dings RP, et al. Among authors: mayo kh. J Natl Cancer Inst. 2006 Jul 5;98(13):932-6. doi: 10.1093/jnci/djj247. J Natl Cancer Inst. 2006. PMID: 16818857

6

Topomimetics of amphipathic beta-sheet and helix-forming bactericidal peptides neutralize lipopolysaccharide endotoxins.

Chen X, Dings RP, Nesmelova I, Debbert S, Haseman JR, Maxwell J, Hoye TR, Mayo KH. Chen X, et al. Among authors: mayo kh. J Med Chem. 2006 Dec 28;49(26):7754-65. doi: 10.1021/jm0610447. J Med Chem. 2006. PMID: 17181157 Free PMC article.

7

Scheduling of radiation with angiogenesis inhibitors anginex and Avastin improves therapeutic outcome via vessel normalization.

Dings RP, Loren M, Heun H, McNiel E, Griffioen AW, Mayo KH, Griffin RJ. Dings RP, et al. Among authors: mayo kh. Clin Cancer Res. 2007 Jun 1;13(11):3395-402. doi: 10.1158/1078-0432.CCR-06-2441. Clin Cancer Res. 2007. PMID: 17545548 Free PMC article.

8

A journey in structure-based drug discovery: from designed peptides to protein surface topomimetics as antibiotic and antiangiogenic agents.

Dings RP, Mayo KH. Dings RP, et al. Among authors: mayo kh. Acc Chem Res. 2007 Oct;40(10):1057-65. doi: 10.1021/ar700086k. Epub 2007 Jul 28. Acc Chem Res. 2007. PMID: 17661438

9

Inhibiting tumor growth by targeting tumor vasculature with galectin-1 antagonist anginex conjugated to the cytotoxic acylfulvene, 6-hydroxylpropylacylfulvene.

Dings RP, Van Laar ES, Loren M, Webber J, Zhang Y, Waters SJ, Macdonald JR, Mayo KH. Dings RP, et al. Among authors: mayo kh. Bioconjug Chem. 2010 Jan;21(1):20-7. doi: 10.1021/bc900287y. Bioconjug Chem. 2010. PMID: 20020769

10

Antitumor agent calixarene 0118 targets human galectin-1 as an allosteric inhibitor of carbohydrate binding.

Dings RP, Miller MC, Nesmelova I, Astorgues-Xerri L, Kumar N, Serova M, Chen X, Raymond E, Hoye TR, Mayo KH. Dings RP, et al. Among authors: mayo kh. J Med Chem. 2012 Jun 14;55(11):5121-9. doi: 10.1021/jm300014q. Epub 2012 May 30. J Med Chem. 2012. PMID: 22575017 Free PMC article.

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