Brat D - Search Results

1

Tuberous sclerosis-associated neoplasms express activated p42/44 mitogen-activated protein (MAP) kinase, and inhibition of MAP kinase signaling results in decreased in vivo tumor growth.

Govindarajan B, Mizesko MC, Miller MS, Onda H, Nunnelley M, Casper K, Brat D, Cohen C, Arbiser JL. Govindarajan B, et al. Among authors: brat d. Clin Cancer Res. 2003 Aug 15;9(9):3469-75. Clin Cancer Res. 2003. PMID: 12960139

2

Tuberous sclerosis-associated lesions of the kidney, brain, and skin are angiogenic neoplasms.

Arbiser JL, Brat D, Hunter S, D'Armiento J, Henske EP, Arbiser ZK, Bai X, Goldberg G, Cohen C, Weiss SW. Arbiser JL, et al. Among authors: d armiento j, brat d. J Am Acad Dermatol. 2002 Mar;46(3):376-80. doi: 10.1067/mjd.2002.120530. J Am Acad Dermatol. 2002. PMID: 11862172

3

Transgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain.

Govindarajan B, Brat DJ, Csete M, Martin WD, Murad E, Litani K, Cohen C, Cerimele F, Nunnelley M, Lefkove B, Yamamoto T, Lee C, Arbiser JL. Govindarajan B, et al. Among authors: brat dj. J Biol Chem. 2005 Feb 18;280(7):5870-4. doi: 10.1074/jbc.M411768200. Epub 2004 Dec 2. J Biol Chem. 2005. PMID: 15576369 Free article.

4

Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization.

Bhatia B, Northcott PA, Hambardzumyan D, Govindarajan B, Brat DJ, Arbiser JL, Holland EC, Taylor MD, Kenney AM. Bhatia B, et al. Among authors: brat dj. Cancer Res. 2009 Sep 15;69(18):7224-34. doi: 10.1158/0008-5472.CAN-09-1299. Epub 2009 Sep 8. Cancer Res. 2009. PMID: 19738049 Free PMC article.

5

Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population.

Brat DJ, Castellano-Sanchez AA, Hunter SB, Pecot M, Cohen C, Hammond EH, Devi SN, Kaur B, Van Meir EG. Brat DJ, et al. Cancer Res. 2004 Feb 1;64(3):920-7. doi: 10.1158/0008-5472.can-03-2073. Cancer Res. 2004. PMID: 14871821

6

Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling.

Kang HB, Fan J, Lin R, Elf S, Ji Q, Zhao L, Jin L, Seo JH, Shan C, Arbiser JL, Cohen C, Brat D, Miziorko HM, Kim E, Abdel-Wahab O, Merghoub T, Fröhling S, Scholl C, Tamayo P, Barbie DA, Zhou L, Pollack BP, Fisher K, Kudchadkar RR, Lawson DH, Sica G, Rossi M, Lonial S, Khoury HJ, Khuri FR, Lee BH, Boggon TJ, He C, Kang S, Chen J. Kang HB, et al. Among authors: brat d. Mol Cell. 2015 Aug 6;59(3):345-358. doi: 10.1016/j.molcel.2015.05.037. Epub 2015 Jul 2. Mol Cell. 2015. PMID: 26145173 Free PMC article.

7

Microphthalmia transcription factor immunohistochemistry: a useful diagnostic marker in the diagnosis and detection of cutaneous melanoma, sentinel lymph node metastases, and extracutaneous melanocytic neoplasms.

O'Reilly FM, Brat DJ, McAlpine BE, Grossniklaus HE, Folpe AL, Arbiser JL. O'Reilly FM, et al. Among authors: brat dj. J Am Acad Dermatol. 2001 Sep;45(3):414-9. doi: 10.1067/mjd.2001.117526. J Am Acad Dermatol. 2001. PMID: 11511840

8

Proliferation (MIB-1 expression) in oligodendrogliomas: assessment of quantitative methods and prognostic significance.

Coleman KE, Brat DJ, Cotsonis GA, Lawson D, Cohen C. Coleman KE, et al. Among authors: brat dj. Appl Immunohistochem Mol Morphol. 2006 Mar;14(1):109-14. doi: 10.1097/01.pai.0000144557.31747.b9. Appl Immunohistochem Mol Morphol. 2006. PMID: 16540741

9

Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity.

Rong Y, Belozerov VE, Tucker-Burden C, Chen G, Durden DL, Olson JJ, Van Meir EG, Mackman N, Brat DJ. Rong Y, et al. Cancer Res. 2009 Mar 15;69(6):2540-9. doi: 10.1158/0008-5472.CAN-08-1547. Epub 2009 Mar 10. Cancer Res. 2009. PMID: 19276385 Free PMC article.

10

Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism.

Kaur B, Cork SM, Sandberg EM, Devi NS, Zhang Z, Klenotic PA, Febbraio M, Shim H, Mao H, Tucker-Burden C, Silverstein RL, Brat DJ, Olson JJ, Van Meir EG. Kaur B, et al. Cancer Res. 2009 Feb 1;69(3):1212-20. doi: 10.1158/0008-5472.CAN-08-1166. Epub 2009 Jan 27. Cancer Res. 2009. PMID: 19176395 Free PMC article.

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