Windsor W - Search Results

1

Improving tolerance of Candida antarctica lipase B towards irreversible thermal inactivation through directed evolution.

Zhang N, Suen WC, Windsor W, Xiao L, Madison V, Zaks A. Zhang N, et al. Among authors: windsor w. Protein Eng. 2003 Aug;16(8):599-605. doi: 10.1093/protein/gzg074. Protein Eng. 2003. PMID: 12968077

2

Structure-guided discovery of cyclin-dependent kinase inhibitors.

Fischmann TO, Hruza A, Duca JS, Ramanathan L, Mayhood T, Windsor WT, Le HV, Guzi TJ, Dwyer MP, Paruch K, Doll RJ, Lees E, Parry D, Seghezzi W, Madison V. Fischmann TO, et al. Among authors: windsor wt. Biopolymers. 2008 May;89(5):372-9. doi: 10.1002/bip.20868. Biopolymers. 2008. PMID: 17937404

3

A point mutation of human interferon gamma abolishes receptor recognition.

Lunn CA, Fossetta J, Dalgarno D, Murgolo N, Windsor W, Zavodny PJ, Narula SK, Lundell D. Lunn CA, et al. Among authors: windsor w. Protein Eng. 1992 Apr;5(3):253-7. doi: 10.1093/protein/5.3.253. Protein Eng. 1992. PMID: 1409546

4

High-level expression, purification, kinetic characterization and crystallization of protein farnesyltransferase beta-subunit C-terminal mutants.

Wu Z, Demma M, Strickland CL, Syto R, Le HV, Windsor WT, Weber PC. Wu Z, et al. Among authors: windsor wt. Protein Eng. 1999 Apr;12(4):341-8. doi: 10.1093/protein/12.4.341. Protein Eng. 1999. PMID: 10325405

5

Modulating the interaction between CDK2 and cyclin A with a quinoline-based inhibitor.

Deng Y, Shipps GW Jr, Zhao L, Siddiqui MA, Popovici-Muller J, Curran PJ, Duca JS, Hruza AW, Fischmann TO, Madison VS, Zhang R, McNemar CW, Mayhood TW, Syto R, Annis A, Kirschmeier P, Lees EM, Parry DA, Windsor WT. Deng Y, et al. Among authors: windsor wt. Bioorg Med Chem Lett. 2014 Jan 1;24(1):199-203. doi: 10.1016/j.bmcl.2013.11.041. Epub 2013 Nov 23. Bioorg Med Chem Lett. 2014. PMID: 24332088

6

Double-stranded DNA-induced localized unfolding of HCV NS3 helicase subdomain 2.

Liu D, Windsor WT, Wyss DF. Liu D, et al. Protein Sci. 2003 Dec;12(12):2757-67. doi: 10.1110/ps.03280803. Protein Sci. 2003. PMID: 14627736 Free PMC article.

7

Discovery of novel, dual mechanism ERK inhibitors by affinity selection screening of an inactive kinase.

Deng Y, Shipps GW Jr, Cooper A, English JM, Annis DA, Carr D, Nan Y, Wang T, Zhu HY, Chuang CC, Dayananth P, Hruza AW, Xiao L, Jin W, Kirschmeier P, Windsor WT, Samatar AA. Deng Y, et al. Among authors: windsor wt. J Med Chem. 2014 Nov 13;57(21):8817-26. doi: 10.1021/jm500847m. Epub 2014 Oct 22. J Med Chem. 2014. PMID: 25313996

8

Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology.

Boga SB, Alhassan AB, Cooper AB, Doll R, Shih NY, Shipps G, Deng Y, Zhu H, Nan Y, Sun R, Zhu L, Desai J, Patel M, Muppalla K, Gao X, Wang J, Yao X, Kelly J, Gudipati S, Paliwal S, Tsui HC, Wang T, Sherborne B, Xiao L, Hruza A, Buevich A, Zhang LK, Hesk D, Samatar AA, Carr D, Long B, Black S, Dayananth P, Windsor W, Kirschmeier P, Bishop R. Boga SB, et al. Among authors: windsor w. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2029-2034. doi: 10.1016/j.bmcl.2018.04.063. Epub 2018 Apr 26. Bioorg Med Chem Lett. 2018. PMID: 29748051

9

Expression and purification of phosphorylated and non-phosphorylated human MEK1.

Smith CK, Carr D, Mayhood TW, Jin W, Gray K, Windsor WT. Smith CK, et al. Among authors: windsor wt. Protein Expr Purif. 2007 Apr;52(2):446-56. doi: 10.1016/j.pep.2006.11.002. Epub 2006 Nov 9. Protein Expr Purif. 2007. PMID: 17175166

10

Farnesyl protein transferase: identification of K164 alpha and Y300 beta as catalytic residues by mutagenesis and kinetic studies.

Wu Z, Demma M, Strickland CL, Radisky ES, Poulter CD, Le HV, Windsor WT. Wu Z, et al. Among authors: windsor wt. Biochemistry. 1999 Aug 31;38(35):11239-49. doi: 10.1021/bi990583t. Biochemistry. 1999. PMID: 10471273

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