Zaks A - Search Results

1

Improving tolerance of Candida antarctica lipase B towards irreversible thermal inactivation through directed evolution.

Zhang N, Suen WC, Windsor W, Xiao L, Madison V, Zaks A. Zhang N, et al. Among authors: zaks a. Protein Eng. 2003 Aug;16(8):599-605. doi: 10.1093/protein/gzg074. Protein Eng. 2003. PMID: 12968077

2

Improved activity and thermostability of Candida antarctica lipase B by DNA family shuffling.

Suen WC, Zhang N, Xiao L, Madison V, Zaks A. Suen WC, et al. Among authors: zaks a. Protein Eng Des Sel. 2004 Feb;17(2):133-40. doi: 10.1093/protein/gzh017. Epub 2004 Jan 12. Protein Eng Des Sel. 2004. PMID: 15047909

3

Industrial biocatalysis.

Zaks A. Zaks A. Curr Opin Chem Biol. 2001 Apr;5(2):130-6. doi: 10.1016/s1367-5931(00)00181-2. Curr Opin Chem Biol. 2001. PMID: 11282338 Review.

4

Preparative synthesis of drug metabolites using human cytochrome P450s 3A4, 2C9 and 1A2 with NADPH-P450 reductase expressed in Escherichia coli.

Vail RB, Homann MJ, Hanna I, Zaks A. Vail RB, et al. Among authors: zaks a. J Ind Microbiol Biotechnol. 2005 Feb;32(2):67-74. doi: 10.1007/s10295-004-0202-1. Epub 2005 Mar 1. J Ind Microbiol Biotechnol. 2005. PMID: 15739102

5

Enzymatic kinetic resolution of piperidine atropisomers: synthesis of a key intermediate of the farnesyl protein transferase inhibitor, SCH66336.

Morgan B, Zaks A, Dodds DR, Liu J, Jain R, Megati S, Njoroge FG, Girijavallabhan VM. Morgan B, et al. Among authors: zaks a. J Org Chem. 2000 Sep 8;65(18):5451-9. doi: 10.1021/jo991513v. J Org Chem. 2000. PMID: 10970281

6

Biotransformations in the discovery and development of pharmaceuticals.

Zaks A, Dodds DR. Zaks A, et al. Curr Opin Drug Discov Devel. 1998 Nov;1(3):290-303. Curr Opin Drug Discov Devel. 1998. PMID: 19649804 No abstract available.

7

Enzymatic glucuronidation of a novel cholesterol absorption inhibitor, Sch 58235.

Zaks A, Dodds DR. Zaks A, et al. Appl Biochem Biotechnol. 1998 May-Jun;73(2-3):205-14. doi: 10.1007/BF02785656. Appl Biochem Biotechnol. 1998. PMID: 9779577

8

Asymmetric Synthesis of Substituted 2-Azaspiro[3.5]nonan-1-ones: An Enantioselective Synthesis of the Cholesterol Absorption Inhibitor (+)-SCH 54016.

Chen LY, Zaks A, Chackalamannil S, Dugar S. Chen LY, et al. Among authors: zaks a. J Org Chem. 1996 Nov 15;61(23):8341-8343. doi: 10.1021/jo961096b. J Org Chem. 1996. PMID: 11667833 No abstract available.

9

An enzymatic synthesis of glucuronides of azetidinone-based cholesterol absorption inhibitors.

Reiss P, Burnett DA, Zaks A. Reiss P, et al. Among authors: zaks a. Bioorg Med Chem. 1999 Oct;7(10):2199-202. doi: 10.1016/s0968-0896(99)00151-0. Bioorg Med Chem. 1999. PMID: 10579526

10

Efficient, chemoenzymatic process for manufacture of the Boceprevir bicyclic [3.1.0]proline intermediate based on amine oxidase-catalyzed desymmetrization.

Li T, Liang J, Ambrogelly A, Brennan T, Gloor G, Huisman G, Lalonde J, Lekhal A, Mijts B, Muley S, Newman L, Tobin M, Wong G, Zaks A, Zhang X. Li T, et al. Among authors: zaks a. J Am Chem Soc. 2012 Apr 11;134(14):6467-72. doi: 10.1021/ja3010495. Epub 2012 Mar 28. J Am Chem Soc. 2012. PMID: 22409428

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