Dean NM - Search Results

1

Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia.

Carter BZ, Milella M, Tsao T, McQueen T, Schober WD, Hu W, Dean NM, Steelman L, McCubrey JA, Andreeff M. Carter BZ, et al. Among authors: dean nm. Leukemia. 2003 Nov;17(11):2081-9. doi: 10.1038/sj.leu.2403113. Leukemia. 2003. PMID: 12970762

2

Regulation and targeting of Eg5, a mitotic motor protein in blast crisis CML: overcoming imatinib resistance.

Carter BZ, Mak DH, Shi Y, Schober WD, Wang RY, Konopleva M, Koller E, Dean NM, Andreeff M. Carter BZ, et al. Among authors: dean nm. Cell Cycle. 2006 Oct;5(19):2223-9. doi: 10.4161/cc.5.19.3255. Epub 2006 Oct 1. Cell Cycle. 2006. PMID: 16969080

3

Inhibition of Bcl-xL expression sensitizes T-cell acute lymphoblastic leukemia cells to chemotherapeutic drugs.

Broome HE, Yu AL, Diccianni M, Camitta BM, Monia BP, Dean NM. Broome HE, et al. Among authors: dean nm. Leuk Res. 2002 Mar;26(3):311-6. doi: 10.1016/s0145-2126(01)00118-7. Leuk Res. 2002. PMID: 11792421

4

Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1.

Gysin S, Lee SH, Dean NM, McMahon M. Gysin S, et al. Among authors: dean nm. Cancer Res. 2005 Jun 1;65(11):4870-80. doi: 10.1158/0008-5472.CAN-04-2848. Cancer Res. 2005. PMID: 15930308

5

Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival.

Flynn P, Wongdagger M, Zavar M, Dean NM, Stokoe D. Flynn P, et al. Among authors: dean nm. Curr Biol. 2000 Nov 16;10(22):1439-42. doi: 10.1016/s0960-9822(00)00801-0. Curr Biol. 2000. PMID: 11102805 Free article.

6

Reversal of cisplatin resistance in human ovarian cancer cell lines by a c-jun antisense oligodeoxynucleotide (ISIS 10582): evidence for the role of transcription factor overexpression in determining resistant phenotype.

Pan B, Yao KS, Monia BP, Dean NM, McKay RA, Hamilton TC, O'Dwyer PJ. Pan B, et al. Among authors: dean nm. Biochem Pharmacol. 2002 May 1;63(9):1699-707. doi: 10.1016/s0006-2952(02)00841-9. Biochem Pharmacol. 2002. PMID: 12007573

7

Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells.

Rosen K, Rak J, Leung T, Dean NM, Kerbel RS, Filmus J. Rosen K, et al. Among authors: dean nm. J Cell Biol. 2000 Apr 17;149(2):447-56. doi: 10.1083/jcb.149.2.447. J Cell Biol. 2000. PMID: 10769035 Free PMC article.

8

Protein kinase Cdelta overexpression enhances radiation sensitivity via extracellular regulated protein kinase 1/2 activation, abolishing the radiation-induced G(2)-M arrest.

Lee YJ, Soh JW, Dean NM, Cho CK, Kim TH, Lee SJ, Lee YS. Lee YJ, et al. Among authors: dean nm. Cell Growth Differ. 2002 May;13(5):237-46. Cell Growth Differ. 2002. PMID: 12065247

9

Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oligonucleotides.

Stewart AJ, Canitrot Y, Baracchini E, Dean NM, Deeley RG, Cole SP. Stewart AJ, et al. Among authors: dean nm. Biochem Pharmacol. 1996 Feb 23;51(4):461-9. doi: 10.1016/0006-2952(95)02220-1. Biochem Pharmacol. 1996. PMID: 8619891

10

Identification of human polo-like kinase 1 as a potential therapeutic target in pancreatic cancer.

Gray PJ Jr, Bearss DJ, Han H, Nagle R, Tsao MS, Dean N, Von Hoff DD. Gray PJ Jr, et al. Mol Cancer Ther. 2004 May;3(5):641-6. Mol Cancer Ther. 2004. PMID: 15141022

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