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Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury.
Yatsiv I, Morganti-Kossmann MC, Perez D, Dinarello CA, Novick D, Rubinstein M, Otto VI, Rancan M, Kossmann T, Redaelli CA, Trentz O, Shohami E, Stahel PF. Yatsiv I, et al. Among authors: stahel pf. J Cereb Blood Flow Metab. 2002 Aug;22(8):971-8. doi: 10.1097/00004647-200208000-00008. J Cereb Blood Flow Metab. 2002. PMID: 12172382
Closed head injury--an inflammatory disease?
Schmidt OI, Heyde CE, Ertel W, Stahel PF. Schmidt OI, et al. Among authors: stahel pf. Brain Res Brain Res Rev. 2005 Apr;48(2):388-99. doi: 10.1016/j.brainresrev.2004.12.028. Epub 2005 Jan 28. Brain Res Brain Res Rev. 2005. PMID: 15850678 Review.
Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines.
Stahel PF, Shohami E, Younis FM, Kariya K, Otto VI, Lenzlinger PM, Grosjean MB, Eugster HP, Trentz O, Kossmann T, Morganti-Kossmann MC. Stahel PF, et al. J Cereb Blood Flow Metab. 2000 Feb;20(2):369-80. doi: 10.1097/00004647-200002000-00019. J Cereb Blood Flow Metab. 2000. PMID: 10698075
Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury.
Leinhase I, Schmidt OI, Thurman JM, Hossini AM, Rozanski M, Taha ME, Scheffler A, John T, Smith WR, Holers VM, Stahel PF. Leinhase I, et al. Among authors: stahel pf. Exp Neurol. 2006 Jun;199(2):454-64. doi: 10.1016/j.expneurol.2006.01.033. Epub 2006 Mar 20. Exp Neurol. 2006. PMID: 16545803
269 results